A recent study published in the British Journal of Medicine has investigated the connection between maternal use of selective serotonin reuptake inhibitor drugs (SSRIs) such as Zoloft®, Paxil®, Prozac®, Celexa®, and Lexapro® during pregnancy and the development of persistent pulmonary hypertension in the newborn. This study, published by Helle Kieler et al. corroborates earlier research
Zoloft Birth Defects
American Journal of Psychiatry Illustrates Danger of Antidepressant Use during Pregnancy
A study published in 2002 in the American Journal of Psychiatry by Dr. Gregory E. Simon, et al. goes great lengths to elucidate the danger of maternal use of antidepressant drugs during pregnancy. In this study, Simon gathered data from the Group Health Corporation, “a prepaid health plan serving approximately 400,000 members in Washington…
Study Shows Danger of SSRIs When Used During Pregnancy
A recent study published in the Archives of General Psychiatry set out to determine whether it was worse for a developing fetus to be exposed to antidepressant drugs during gestation or to be carried to term by a mother-to-be who suffered from depression during pregnancy. This study, published by Dr. Tim F. Oberlander et al.…
Study Shows Antidepressant Use During Pregnancy Leads to More Birth Defects
In 2010, a Danish study published in the medical journal Clinical Epidemiology set out to evaluate the danger posed to infants born to mothers who used selective serotonin reuptake inhibitors (SSRIs, a new class of antidepressant drugs including Zoloft®, Paxil®, and Prozac®) during early pregnancy.
The study, published by Jette B. Kornum et al.…
Study Shows SSRI Use during Pregnancy Doubles Risk of Birth Defects
Published in a 2011 edition of the medical journal Obstetrics and Gynecology, a study by Dr. Heli Malm (et al.) evaluated the risk of birth defects for children born to mothers who used selective serotonin-reuptake inhibitors (a type of antidepressant medication) during pregnancy. Drugs whose danger was evaluated included fluoxetine (Prozac®, Sarafem®,…
Pulmonary Valve Stenosis
A birth defect of the heart recently found to be associated with maternal use of SSRI drugs during pregnancy,[1] pulmonary valve stenosis is characterized by a narrowing (stenosis) of the pulmonary valve of the heart, the valve which opens to allow blood to flow from the right ventricle to the lungs for oxygenation.[2]…
Transposition of the Great Arteries
Transposition of the Great Arteries is a congenital (present at birth) heart defect found to be associated with maternal use of Prozac® during pregnancy by medical researcher Diav-Citrin in a 2008 study titled “Paroxetine and fluoxetine in pregnancy: a prospective, multicentre, controlled, observational study,” published in the British Journal of Clinical Pharmacology.
Concerning persons suffering…
Tricuspid Valve Stenosis
Tricuspid valve stenosis is a heart defect present at birth in some infants. “In this condition, the tricuspid valve is narrowed, decreasing the amount of blood that can flow through it from the right atrium to the right ventricle.”[1]

When blood flow to the right ventricle…
SSRI Use during Pregnancy Raises Risk of Serious Birth Defects
In a study published in a 2007 edition of the New England Journal of Medicine, Sura Alwan et al. evaluates the effect of maternal use of selective serotonin reuptake inhibitor medications (SSRIs) during pregnancy on the likelihood of bearing children with congenital malformations. The study, titled “Use of Selective Serotonin Reuptake Inhibitors in Pregnancy…
WebMD – Mothers Who Switch SSRIs During Pregnancy Place Newborns at Risk of Heart Defects
It has been recently found that babies of mothers who filled prescriptions for more than one SSRI during pregnancy were four times as likely to be born with septal heart defects as were other babies born to mothers who did not use SSRIs during pregnancy. If uncorrected, this birth defect, characterized by a malformation of…