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Dangerous Drugs & Medical Devices News & Commentary on Prescription Drug & Medical Device Lawsuits

2011 – Study links Propecia, Proscar to adverse sexual side effects

Posted in Propecia / Proscar

Published in 2011 – over a year prior to Propecia Warning Label Updates, a paper by A.M. Traish et al. titled “Adverse side effects of 5α-reductase inhibitors therapy: persistent diminished libido and erectile dysfunction and depression in a subset of patients.” illustrated important connections between chemicals like finasteride (the active ingredient in drugs Propecia and Proscar) and adverse sexual side effects such as decreased libido, erectile dysfunction, and others.

The team writes “5α-reductase inhibitors (5α-RIs), finasteride and dutasteride, have been approved for treatment of lower urinary tract symptoms, due to benign prostatic hyperplasia, with marked clinical efficacy. Finasteride is also approved for treatment of hair loss (androgenetic alopecia). Although the adverse side effects of these agents are thought to be minimal, the magnitude of adverse effects on sexual function, gynecomastia, depression, and quality of life remains ill-defined.”  As such, the goal of this report was to “discuss 5α-RIs therapy, the potential persistent side effects, and the possible mechanisms responsible for these undesirable effects.”

Among men who used finasteride, the team found that “Prolonged adverse effects on sexual function such as erectile dysfunction and diminished libido are reported by a subset of men, raising the possibility of a causal relationship.”  Traish et al. (2011) suggest “discussion with patients on the potential sexual side effects of 5α-RIs before commencing therapy” and advocate for alternative therapy when applicable.

Due to the fact that a number of men have used Propecia and other finasteride-containing drugs unaware of the risk for adverse sexual side effects, a number of Propecia lawsuits have been filed.  If you or a loved one used Propecia or Proscar and suffered adverse sexual side effects, you too may be entitled to significant financial compensation.  For a free, no-obligation case consultation, contact our team of Proscar lawyers and Propecia lawyers at the information provided below.  We have the experience, resources, and skills required to win the justice you deserve.  Call today and see how we can help.

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