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Category Archives: SSRI Birth Defects

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2011 – SSRI use linked to 5-fold increased risk for preterm birth

Posted in SSRI Birth Defects

In December 2011, a team of medical researchers led by A. Roca from Barcelona published an article in Journal of Affective Disorders titled “Obstetrical and neonatal outcomes after prenatal exposure to selective serotonin reuptake inhibitors: the relevance of dose.”, with the purpose of evaluating “the effects of prenatal exposure to selective serotonin reuptake inhibitors (SSRIs)… Continue Reading

2012 – Another study shows SSRIs in pregnancy raise risk for premature birth

Posted in SSRI Birth Defects

Nearly two years ago, an article titled “Depression and serotonin reuptake inhibitor treatment as risk factors for preterm birth.” by K.A. Yonkers and a team of researchers from Yale University School of Medicine appeared in Epidemiology exploring the relationship between selective serotonin reuptake inhibitor drugs (SSRIs) and increased risk for preterm birth.  This article, along… Continue Reading

2014 – SSRIs again linked to heart defects

Posted in SSRI Birth Defects

An article published last month in The New England Journal of Medicine further examined the link between gestational exposure to SSRI drugs and increased risk for serious heart defects.  This article, was titled “Antidepressant use in pregnancy and the risk of cardiac defects.”, a study performed by K.F. Huybrechts et al. As have many other… Continue Reading

2013 – Autism linked to maternal SSRI use

Posted in SSRI Birth Defects

In April, 2013, a team of researchers from the University of Bristol led by D. Rai published a study in British Medical Journal titled “Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study.” that explored the link between maternal antidepressant use in pregnancy and increased risk for… Continue Reading

2009 – Premature birth risk increased by mother’s SSRI use

Posted in SSRI Birth Defects

In October 2009, an article by N. Lund et al. titled “Selective serotonin reuptake inhibitor exposure in utero and pregnancy outcomes.” was published in Archives of Pediatrics and Adolescent Medicine that intended “To investigate the effect of intrauterine selective serotonin reuptake inhibitor (SSRI) exposure on pregnancy outcomes.”  Included in this class of medications are drugs… Continue Reading

2009 – Research shows premature birth more likely with prenatal SSRI exposure

Posted in SSRI Birth Defects

A December, 2009 article published in Journal of Clinical Psychopharmacology by S. Toh et al., titled “Antidepressant use during pregnancy and the risk of preterm delivery and fetal growth restriction” describes some of the potential adverse effects of prenatal exposure to a pregnant mother’s antidepressant drugs. Toh et al. (2009) state that “Analysis included women… Continue Reading

2005 – Spontaneous abortion more likely with gestational SSRI exposure

Posted in SSRI Birth Defects

Today, I found an article titled “Antidepressant use during pregnancy and the rates of spontaneous abortions: a meta-analysis.” that first appeared in the May, 2005 edition of The Annals of Psychopharmacology by M.E. Hemels et al., which attempted to determine “baseline rates of spontaneous abortions (SAs) [in the general population] and whether antidepressants increase those… Continue Reading

2005 – Study reviews Prozac’s effects on fetal development

Posted in Prozac Birth Defects, SSRI Birth Defects

Published in a 2005 edition of Reproduction, fertility, and development, an article titled “Fluoxetine during pregnancy: impact on fetal development.” by JL Morrison and a team of researchers from University of Adelaide (Australia) explored the connection between prenatal exposure to pregnancySSRI drugs and adverse birth outcomes including birth defects. The team explains that, “Women are… Continue Reading

2006 – Pulmonary Hypertension Linked to SSRI Exposure in Pregnancy

Posted in SSRI Birth Defects

In 2006, C.D. Chambers et al. published a study titled “Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn.” in The New England Journal of Medicine, further evaluating the connection between SSRI exposure and birth defects.  Here, the link between SSRI drugs and persistent pulmonary hypertension of the newborn (PPHN) is explored…. Continue Reading

2007 – Prozac linked to adverse birth outcomes in mice

Posted in Prozac Birth Defects, SSRI Birth Defects

Titled “Behavioral evaluation of male and female mice pups exposed to fluoxetine during pregnancy and lactation.”, an article by SF Lisboa and a team of researchers from State University of Londrina (Londrina, Brazil) that appeared in Pharmacology (2007) illustrates reasons to avoid Prozac use during pregnancy.  For clarity, “fluoxetine” is the chemical name for Prozac…. Continue Reading

2000 – SSRI exposure linked to craniofacial birth defects

Posted in SSRI Birth Defects

I recently came across a 2000 article from University of North Carolina, Chapel Hill by J.R. Moiseiwitsch et al., titled “The role of serotonin and neurotransmitters during craniofacial development.”.  This article, published in Critical Reviews in Oral Biology and Medicine, demonstrates how prenatal exposure to SSRI drugs affects craniofacial development, all too often resulting in… Continue Reading

American Journal of Psychiatry (2002) – SSRIs in pregnancy linked to deadly birth defects

Posted in SSRI Birth Defects

Over the past two decades, a number of medical research teams have linked SSRI use during pregnancy and birth defects, developmental disorders like autism, and adverse birth outcomes such as neonatal abstinence syndrome.  And, a December 2002 article in American Journal of Psychiatry titled “Outcomes of prenatal antidepressant exposure.” published by a team led by… Continue Reading

2002 – SSRIs linked to low birth weight, premature birth

Posted in SSRI Birth Defects

Over the past two decades, a number of medical research teams have linked SSRI use during pregnancy and birth defects, developmental disorders like autism, and adverse birth outcomes such as neonatal abstinence syndrome.  And, a December 2002 article in American Journal of Psychiatry titled “Outcomes of prenatal antidepressant exposure.” published by a team led by… Continue Reading

2009 – Doctors caution against use of SSRI drugs during pregnancy

Posted in SSRI Birth Defects

In June, 2009, Current Psychiatry Reports published an article titled “Selective serotonin reuptake inhibitor use during pregnancy and possible neonatal complications.” by J. Cantor Sackett et al. from The Thomas Jefferson University Hospital in Philadelphia that evaluated the use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy.  SSRI drugs are antidepressants such as Prozac, Zoloft,… Continue Reading

2008 – SSRIs linked to heart defect ASD

Posted in SSRI Birth Defects

Today, I found an article titled “Major congenital malformations following prenatal exposure to serotonin reuptake inhibitors and benzodiazepines using population-based health data.” that originally appeared in the February, 2008 edition of Birth Defects Research.  This insightful piece of research by TF Oberlander and a team of researchers from The University of British Columbia (Vancouver) provides… Continue Reading

If trace Zoloft in the water supply can hurt tadpoles, how do you think it affects your baby when you eat it?

Posted in SSRI Birth Defects, Zoloft Birth Defects

Titled “Growth and development of tadpoles (Xenopus laevis) exposed to selective serotonin reuptake inhibitors, fluoxetine and sertraline, throughout metamorphosis.,” an article by D.E. Conners and a team from The Department of Environmental Health Science at University of Georgia has demonstrated that Prozac and Zoloft in the water supply can inhibit the development of tadpoles.  While… Continue Reading

2009 – More research links SSRIs with birth defects: heart defects, adverse birth outcomes

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

In 2009, S. Alwan and J.M. Friedman, a research duo from the University of British Columbia in Vancouver, published a study titled “Safety of selective serotonin reuptake inhibitors in pregnancy.” in CNS Drugs that provided important insight into the link between gestational exposure to selective serotonin reuptake inhibitor drugs (such as Prozac, Paxil, and Zoloft)… Continue Reading

2010 – Infantile Hypertrophic Pyloric Stenosis (IHPS) linked to Prozac exposure

Posted in Prozac Birth Defects, SSRI Birth Defects

Today, I came across an article from the Netherlands by M.K. Bakker published in Pharmacoepidemiology and Drug Safety (August, 2010) titled “Fluoxetine and infantile hypertrophic pylorus stenosis: a signal from a birth defects-drug exposure surveillance study.”, a piece that made great strides in elucidating the connection between prenatal exposure to Prozac (fluoxetine) and serious birth… Continue Reading

2010 – Goldenhar syndrome linked with prenatal Prozac exposure

Posted in Prozac Birth Defects, SSRI Birth Defects

In July 2010, a team of Lebanese published a study titled “Goldenhar syndrome associated with prenatal maternal Fluoxetine ingestion: Cause or coincidence?” in the medical journal Birth Defects Research reviewing a congenital malformation linked to prenatal Prozac (fluoxetine) exposure.  That team, led by C. Farra, was the first to associate goldenhar syndrome with Prozac, though… Continue Reading

Study finds Zoloft exposure linked to heart defects

Posted in SSRI Birth Defects, Zoloft Birth Defects

Today, I found an article published in a 2013 edition of Pediatric Research by S.E. Haskell et al. (a team from University of Iowa Carver College of Medicine) titled “Sertraline exposure leads to small left heart syndrome in adult mice.” that further elucidates the connection between gestational Zoloft exposure and adverse birth outcomes. Haskell writes,… Continue Reading

Prozac-exposed children more likely to have neonatal abstinence syndrome

Posted in Prozac Birth Defects, SSRI Birth Defects

A study published in the September, 2004 edition of The international journal of neuropsyhopharmacology titled “A pilot study of newer antidepressant concentrations in cord and maternal serum and possible effects in the neonate.” by J. Rampono et al. provides further insight into the connection between gestational exposure to selective serotonin reuptake inhibitor drugs and adverse… Continue Reading

Zoloft linked to poor neonatal adaptation

Posted in SSRI Birth Defects, Zoloft Birth Defects

The June, 2004 edition of Journal of Perinatology presented a study titled “Transient neonatal jitteriness due to maternal use of sertraline (Zoloft).” by R.P. Santos et al., providing important insight into the link between Zoloft expousre during pregnancy and adverse birth outcomes.  Here is the abstract of that article: “We describe the occurrence of marked… Continue Reading

2008 – Paxil exposure shows reduced birth weight in rat model

Posted in Paxil Birth Defects, SSRI Birth Defects

In 2008, a team of Dutch researchers led by D.L. Van den Hove published a study in Neonatology titled “Prenatal maternal paroxetine treatment and neonatal mortality in the rat: a preliminary study.” evaluating the perinatal effects of gestational exposure to Paxil (paroxetine). These researchers write, “Recent evidence has shown that prenatal maternal stress has negative… Continue Reading

2011 – Heart defects linked to prenatal Paxil exposure, again

Posted in Paxil Birth Defects, SSRI Birth Defects

Today, I came across an article from the March, 2011 edition of Journal of Population Therapeutics and Clinical Pharmacology titled “The effect of ascertainment bias in evaluating gestational antidepressant exposure.” that helps illustrate the link between gestational exposure to selective serotonin reuptake inhibitor drugs and birth defects, heart defects in particular. Here is the abstract… Continue Reading