In 2012, C.M. Nijenhuis and a team from University of Groningen (Groningen, The Netherlands) published a study titled “Disturbed development of the enteric nervous system after in utero exposure of selective serotonin re-uptake inhibitors and tricyclic antidepressants. Part 1: Literature review.” in British Journal of Clinical Pharmacology. There, the link between gestational
SSRI Birth Defects
2009 – Preterm birth again linked to SSRI exposure before birth
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Recently, I found an article titled “Risk of preterm delivery and other adverse perinatal outcomes in relation to maternal use of psychotropic medications during pregnancy.” that originally appeared in the December 2009 edition of American Journal of Obstetrics and Gynecology. Published by R. Calderon-Margalit and a team from The University of Washington…
SSRIs in pregnancy linked to 12-fold increased risk for preterm birth
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Today, I came across an article published in a 2011 edition of Journal of Midwifery and Women’s Health by G. Latendresse and a team of researchers from The University of Utah College of Nursing (Salt Lake City) titled “Maternal corticotropin-releasing hormone and the use of selective serotonin reuptake inhibitors independently predict the occurrence of…
2011 – Low gestational age linked to SSRI exposure, not maternal depression
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Titled “Newborn neurobehavioral patterns are differentially related to prenatal maternal major depressive disorder and serotonin reuptake inhibitor treatment.”, an article by A.L. Salisbury and a team from the Warren Alpert Medical School of Brown University, appearing in the December, 2011 edition of Depression and Anxiety, further explores the link between selective serotonin…
Neurological function adversely affected by maternal SSRIs
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In May, 2013, N.K. de Vries published an article titled “Early neurological outcome of young infants exposed to selective serotonin reuptake inhibitors during pregnancy: results from the observational SMOK study.” in the medical journal PLoS One. This Dutch research team explored poor neonatal outcomes linked to selective serotonin reuptake inhibitor drugs (SSRIs)…
2011 – Heart development affected by maternal SSRI use
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Published in the July, 2011 edition of Pediatric Research, a study by D. Rurak and a team from The University of British Columbia (Vancouver) titled “Third trimester fetal heart rate and Doppler middle cerebral artery blood flow velocity characteristics during prenatal selective serotonin reuptake inhibitor exposure.” examined the relationship between selective serotonin…
Study shows SSRIs affect fetal neurodevelopment
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From The Netherlands, a team of medical researchers led by E.J. Mulder published a study titled “Selective serotonin reuptake inhibitors affect neurobehavioral development in the human fetus.” in the September, 2011 edition of Neuropsychopharmacology examining the relationship between exposure to selective serotonin reuptake inhibitor drugs (SSRIs) and adverse birth outcomes.
The team…
Autism, poor neurodevelopment linked to SSRIs in pregnancy
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An article titled “SSRI antidepressants: altered psychomotor development following exposure in utero?” that appeared in the February, 2013 edition of Prescrire International examines additional risks of prenatal exposure to selective serotonin reuptake inhibitor drugs (SSRIs). To be clear, a number of other studies have linked adverse birth outcomes linked to SSRI exposure…
2013 – Researchers show that SSRIs (not maternal depression) cause poor neonatal outcomes
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Last summer, a team of researchers from University of British Columbia (Vancouver) led by G.E. Hanley published a study titled “Infant developmental outcomes following prenatal exposure to antidepressants, and maternal depressed mood and positive affect.” in Early Human Development. This study examined the relationship between poor early childhood development and gestational exposure…
Prozac, Pazil, Zoloft, Celexa linked to Persistent Pulmonary Hypertension of the Newborn (PPHN)
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Titled “Further findings linking SSRIs during pregnancy and persistent pulmonary hypertension of the newborn: clinical implications.”, this article appearing in the October, 2012 edition of CNS Drugs by M. Galbally et al., identifies persistent pulmonary hypertension of the newborn (PPHN) as a potential consequence of SSRI exposure before birth.
Galbally et al.