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2013 – Meta-analysis study links SSRIs and poor neonatal outcomes

Posted in SSRI Birth Defects

In April 2013, a team of medical researchers from The Centre for Addiction and Mental Health at The University of Toronto published a study titled “Selected pregnancy and delivery outcomes after exposure to antidepressant medication: a systematic review and meta-analysis.” in JAMA Psychiatry.  This research team, led by L.E. Ross, studied the connection between gestational exposure to selective serotonin reuptake inhibitor drugs (SSRIs) and poor neonatal adaptation.

Ross et al. (2013) state “Untreated depression during pregnancy has been associated with increased morbidity and mortality for both mother and child and, as such, optimal treatment strategies are required for this population” but warn that “There are conflicting data regarding potential risks of prenatal antidepressant treatment.”

This team “reviewed 3074 abstracts, retrieved 735 articles, and included 23 studies in this meta-analysis”.  (A meta-analysis is a study wherein other previously-published studies are reviewed to achieve an understanding of the current state of medical research on a topic.)

Results showed that “Gestational age and preterm delivery were statistically significantly associated with antidepressant exposure” (increased risk – 55%).  And, it was found that “Antidepressant exposure during pregnancy was significantly associated with lower birth weight … Antidepressant exposure was significantly associated with lower [adaptation] scores at 1 and 5 minutes, regardless of whether the comparison group was all mothers or only those who were depressed during pregnancy but not exposed to antidepressants.”

Since many women have used antidepressants in pregnancy unaware of the increased risk for adverse birth outcomes, thousands of SSRI birth defect lawsuits have been filed around the world.  If you or a loved one used SSRIs and gave birth to a child with a congenital malformation or who had perinatal complications, you may be entitled to significant financial compensation.

For a free, no-obligation case consultation, contact our team of SSRI birth defect lawyers at the information provided below.  We have the experience, resources, and skills required to win the justice you deserve.  Call today and see how we can help.

(855) 452 – 5529


Our SSRI Birth Defects Lawsuit Information page is a great place to start if you have any questions about SSRIs and Birth Defects.