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Dangerous Drugs & Medical Devices News & Commentary on Prescription Drug & Medical Device Lawsuits

Monthly Archives: June 2014

American Journal of Psychiatry (2002) – SSRIs in pregnancy linked to deadly birth defects

Posted in SSRI Birth Defects

Over the past two decades, a number of medical research teams have linked SSRI use during pregnancy and birth defects, developmental disorders like autism, and adverse birth outcomes such as neonatal abstinence syndrome.  And, a December 2002 article in American Journal of Psychiatry titled “Outcomes of prenatal antidepressant exposure.” published by a team led by… Continue Reading

2002 – SSRIs linked to low birth weight, premature birth

Posted in SSRI Birth Defects

Over the past two decades, a number of medical research teams have linked SSRI use during pregnancy and birth defects, developmental disorders like autism, and adverse birth outcomes such as neonatal abstinence syndrome.  And, a December 2002 article in American Journal of Psychiatry titled “Outcomes of prenatal antidepressant exposure.” published by a team led by… Continue Reading

2009 – Doctors caution against use of SSRI drugs during pregnancy

Posted in SSRI Birth Defects

In June, 2009, Current Psychiatry Reports published an article titled “Selective serotonin reuptake inhibitor use during pregnancy and possible neonatal complications.” by J. Cantor Sackett et al. from The Thomas Jefferson University Hospital in Philadelphia that evaluated the use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy.  SSRI drugs are antidepressants such as Prozac, Zoloft,… Continue Reading

2008 – SSRIs linked to heart defect ASD

Posted in SSRI Birth Defects

Today, I found an article titled “Major congenital malformations following prenatal exposure to serotonin reuptake inhibitors and benzodiazepines using population-based health data.” that originally appeared in the February, 2008 edition of Birth Defects Research.  This insightful piece of research by TF Oberlander and a team of researchers from The University of British Columbia (Vancouver) provides… Continue Reading

If trace Zoloft in the water supply can hurt tadpoles, how do you think it affects your baby when you eat it?

Posted in SSRI Birth Defects, Zoloft Birth Defects

Titled “Growth and development of tadpoles (Xenopus laevis) exposed to selective serotonin reuptake inhibitors, fluoxetine and sertraline, throughout metamorphosis.,” an article by D.E. Conners and a team from The Department of Environmental Health Science at University of Georgia has demonstrated that Prozac and Zoloft in the water supply can inhibit the development of tadpoles.  While… Continue Reading

2009 – More research links SSRIs with birth defects: heart defects, adverse birth outcomes

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

In 2009, S. Alwan and J.M. Friedman, a research duo from the University of British Columbia in Vancouver, published a study titled “Safety of selective serotonin reuptake inhibitors in pregnancy.” in CNS Drugs that provided important insight into the link between gestational exposure to selective serotonin reuptake inhibitor drugs (such as Prozac, Paxil, and Zoloft)… Continue Reading

2010 – Infantile Hypertrophic Pyloric Stenosis (IHPS) linked to Prozac exposure

Posted in Prozac Birth Defects, SSRI Birth Defects

Today, I came across an article from the Netherlands by M.K. Bakker published in Pharmacoepidemiology and Drug Safety (August, 2010) titled “Fluoxetine and infantile hypertrophic pylorus stenosis: a signal from a birth defects-drug exposure surveillance study.”, a piece that made great strides in elucidating the connection between prenatal exposure to Prozac (fluoxetine) and serious birth… Continue Reading

2010 – Goldenhar syndrome linked with prenatal Prozac exposure

Posted in Prozac Birth Defects, SSRI Birth Defects

In July 2010, a team of Lebanese published a study titled “Goldenhar syndrome associated with prenatal maternal Fluoxetine ingestion: Cause or coincidence?” in the medical journal Birth Defects Research reviewing a congenital malformation linked to prenatal Prozac (fluoxetine) exposure.  That team, led by C. Farra, was the first to associate goldenhar syndrome with Prozac, though… Continue Reading

Study finds Zoloft exposure linked to heart defects

Posted in SSRI Birth Defects, Zoloft Birth Defects

Today, I found an article published in a 2013 edition of Pediatric Research by S.E. Haskell et al. (a team from University of Iowa Carver College of Medicine) titled “Sertraline exposure leads to small left heart syndrome in adult mice.” that further elucidates the connection between gestational Zoloft exposure and adverse birth outcomes. Haskell writes,… Continue Reading

Prozac-exposed children more likely to have neonatal abstinence syndrome

Posted in Prozac Birth Defects, SSRI Birth Defects

A study published in the September, 2004 edition of The international journal of neuropsyhopharmacology titled “A pilot study of newer antidepressant concentrations in cord and maternal serum and possible effects in the neonate.” by J. Rampono et al. provides further insight into the connection between gestational exposure to selective serotonin reuptake inhibitor drugs and adverse… Continue Reading

Zoloft linked to poor neonatal adaptation

Posted in SSRI Birth Defects, Zoloft Birth Defects

The June, 2004 edition of Journal of Perinatology presented a study titled “Transient neonatal jitteriness due to maternal use of sertraline (Zoloft).” by R.P. Santos et al., providing important insight into the link between Zoloft expousre during pregnancy and adverse birth outcomes.  Here is the abstract of that article: “We describe the occurrence of marked… Continue Reading

2008 – Paxil exposure shows reduced birth weight in rat model

Posted in Paxil Birth Defects, SSRI Birth Defects

In 2008, a team of Dutch researchers led by D.L. Van den Hove published a study in Neonatology titled “Prenatal maternal paroxetine treatment and neonatal mortality in the rat: a preliminary study.” evaluating the perinatal effects of gestational exposure to Paxil (paroxetine). These researchers write, “Recent evidence has shown that prenatal maternal stress has negative… Continue Reading

2011 – Heart defects linked to prenatal Paxil exposure, again

Posted in Paxil Birth Defects, SSRI Birth Defects

Today, I came across an article from the March, 2011 edition of Journal of Population Therapeutics and Clinical Pharmacology titled “The effect of ascertainment bias in evaluating gestational antidepressant exposure.” that helps illustrate the link between gestational exposure to selective serotonin reuptake inhibitor drugs and birth defects, heart defects in particular. Here is the abstract… Continue Reading

1997 – Spontaneous abortion seen in 14% of prenatal SSRI exposures

Posted in Prozac Birth Defects, SSRI Birth Defects

Researching the connection between prenatal Prozac exposure and birth defects this morning, I found an article by D.J. Goldstein et al., titled “Effects of first-trimester fluoxetine exposure on the newborn.”  This article, appearing in the May, 1997 edition of Obstetrics and Gynecology, provides important insight into the connection between gestational SSRI exposure and adverse birth… Continue Reading

1996 – Increased risk for miscarriage associated with SSRI use in pregnancy

Posted in SSRI Birth Defects

Today, I read a 1996 study by a team from Georgetown University published in Harvard Review of Psychiatry titled “Selective serotonin-reuptake inhibitors in pregnancy and lactation.”, that provides good insight into the state of research into the SSRI-birth defect link nearly two decades ago. Of their research, the team led by A.L. Baum, states “We… Continue Reading

1996 – Prozac linked to birth defects, premature birth, low birth weight, adverse outcomes

Posted in Prozac Birth Defects, SSRI Birth Defects

Recently, I found an article titled “Birth outcomes in pregnant women taking fluoxetine.”, appearing in the October 1996 edition of The New England Journal of Medicine, amounting to one of the oldest articles studying the link between gestational Prozac exposure and adverse birth outcomes.  Over the past two decades, many studies have been published linking… Continue Reading

1996 – Adverse birth outcomes seen with prenatal Prozac exposure

Posted in Prozac Birth Defects, SSRI Birth Defects

In 1996, C.D. Chambers et al. published a study titled “Birth outcomes in pregnant women taking fluoxetine.” in The New England Journal of Medicine studying the effects of prenatal exposure to Prozac (fluoxetine).  Many studies since have demonstrated that babies born to mothers who used Prozac before birth are much more likely to be born… Continue Reading

1992 – Zoloft, SSRIs linked to craniofacial birth defects

Posted in SSRI Birth Defects, Zoloft Birth Defects

Searching the phrase “sertraline malformation” in PubMed, an online medical literature database curated by the US National Library of Medicine and National Institutes of Health, this morning I came across an article titled “Serotonin as a regulator of craniofacial morphogenesis: site specific malformations following exposure to serotonin uptake inhibitors.” by D.L. Shuey et al., appearing… Continue Reading

Neonatal seizures from Effexor exposure; Effexor, SSRIs present in amniotic fluid

Posted in Effexor Birth Defects, SSRI Birth Defects

Here, I present two studies I read this morning concerning the connection between prenatal SSRI exposure and adverse perinatal outcomes.  selective serotonin reuptake inhibitor drugs (SSRIs) are widely used for a range of psychiatric ailments from depression to anxiety and work by regulating the concentration of serotonin molecules in the synapses between neurons.  Serotonin is… Continue Reading

European researchers find Effexor neonatal withdrawal and newborn intestinal tissue death from exposure

Posted in Effexor Birth Defects, SSRI Birth Defects

Over the past two decades, a number of scientific studies have demonstrated that exposure to selective serotonin reuptake inhibitor drugs (SSRIs) can have adverse effects on a developing fetus.  Here, I’ll reference a pair of European studies that cite these adverse effects. First, an article titled “[Withdrawal symptoms in a neonate following exposure to venlafaxine… Continue Reading

2007 – Study finds increased risk for preterm birth with prenatal SSRI exposure

Posted in SSRI Birth Defects

In the December, 2007 edition of Journal of Clinical Psychopharmacology, a team of Swedish researchers led by R. Lennestål titled “Delivery outcome in relation to maternal use of some recently introduced antidepressants.” explores birth outcomes for babies exposed to antidepressant drugs such as serotonin-noradrenaline reuptake inhibitor drugs (SNRIs) and noradrenergic reuptake inhibitors (NRIs). The team… Continue Reading

2007 – Adverse birth outcomes for babies exposed to Effexor, SSRIs during pregnancy

Posted in Effexor Birth Defects, SSRI Birth Defects

A study titled “Effects of selective serotonin reuptake inhibitors and venlafaxine during pregnancy in term and preterm neonates.” published in the January, 2007 edition of Pediatrics by E. Ferreira et al. made great strides in elucidating the connection between preterm birth and gestational exposure to selective serotonin reuptake inhibitors or Effexor (venlafaxine). The team states,… Continue Reading

2010 – Scientists find link between low birth weight and SSRI exposure

Posted in Effexor Birth Defects, SSRI Birth Defects

An article published in the October, 2010 edition of Canadian Journal of Psychiatry by a team of researchers from Pfizer (Canada), led by É. Ramos, titled “Association between antidepressant use during pregnancy and infants born small for gestational age.” that sheds light on the connection between gestational exposure to SSRI drugs and low birth weight…. Continue Reading