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Dangerous Drugs & Medical Devices News & Commentary on Prescription Drug & Medical Device Lawsuits

Monthly Archives: May 2014

2011 – Study links exposure to Celexa, other SSRIs to birth defects

Posted in Celexa Birth Defects, SSRI Birth Defects

In 2011, a team of medical researchers from Australia led by L. Colvin, published a study titled “Dispensing patterns and pregnancy outcomes for women dispensed selective serotonin reuptake inhibitors in pregnancy.” in Birth Defects Research, providing further evidence of a link between prenatal exposure to SSRI drugs and birth defects.  For clarity, “SSRIs” stands for… Continue Reading

2004 – Risk for low birth weight, preterm birth doubled with Paxil exposure

Posted in Paxil Birth Defects, SSRI Birth Defects

In 2004, an article by B. Källén, a Swedish researcher, titled “Neonate characteristics after maternal use of antidepressants in late pregnancy.” in Archives of Pediatrics and Adolescent Medicine provides insight into the danger of perinatal exposure to selective serotonin reuptake inhibitor drugs (SSRIs). The stated objective was “To investigate neonatal outcomes in 997 infants (987… Continue Reading

2006 – Case of neonatal exposure to Paxil illustrated

Posted in Paxil Birth Defects, SSRI Birth Defects

In 2006, a team of Spanish medical researchers published a report titled “[Neonatal withdrawal syndrome to selective serotonin reuptake inhibitors: case report and literature review].” in Revista de Neurologica, wherein a child who suffered SSRI withdrawal symptoms after birth is presented along with a review of relevant literature.  “SSRI” stands for selective serotonin reuptake inhibitor… Continue Reading

2002 – Babies exposed to Paxil before birth 10 times more likely to have adverse birth outcome

Posted in Paxil Birth Defects, SSRI Birth Defects

A 2002 piece published by A.M. Costei and a team of medical researchers from Toronto in the medical journal Archives of Pediatrics and Adolescent Medicine tited “Perinatal outcome following third trimester exposure to paroxetine.” further demonstrates possible adverse effects of in utero exposure to Paxil.  (“Paroxetine” is the chemical name for Paxil, a selective serotonin… Continue Reading

2006 – FDA Warns Public on Paxil Danger for Neonates

Posted in Paxil Birth Defects, SSRI Birth Defects

In the March-April 2006 edition of Consumer Magazine (of the United States Food and Drug Administration), an important update was provided regarding the safety of selective serotonin reuptake inhibitors for developing babies. Here is the full update, titled “Paxil and the Risk of Birth Defects”: “Early results of new studies for Paxil (paroxetine) suggest that… Continue Reading

2005 – 300% increased risk for neonatal behavioral syndrome with prenatal SSRI exposure

Posted in SSRI Birth Defects

A 2005 study titled “Neonatal signs after late in utero exposure to serotonin reuptake inhibitors: literature review and implications for clinical applications.” published by EL Moses-Kolko et al. in Journal of the American Medical Association sheds light on perinatal complications associated with in utero exposure to selective serotonin reuptake inhibitors (SSRIs). The authors state “A… Continue Reading

Five more studies illustrate the danger of prenatal exposure to SSRI drugs

Posted in Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects

This morning, I found a number of studies on PubMed (a medical research database curated by the US National Library of Medicine and National Institutes of Health) that linked prenatal exposure to selective serotonin reuptake inhibitor drugs (“SSRIs,” for short) and adverse birth outcomes.  Over the past two decades, many researchers have linked SSRI exposure… Continue Reading

Letter to Editor of American Journal of Psychiatry: SSRIs in pregnancy? Err on the side of caution

Posted in SSRI Birth Defects

Recently, while researching the connection between maternal use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy and birth defects, I came across this letter to the editor of The American Journal of Psychiatry.  Titled “Should Paroxetine Be Used to Treat Depression During Pregnancy?”, published November 2008, authors Barbara Mintzes and Jon Jureidini suggest that though… Continue Reading

Many studies link Paxil, SSRI exposure to adverse birth outcomes

Posted in Paxil Birth Defects, SSRI Birth Defects

Looking through PubMed, a medical literature database curated by the National Library of Medicine and the US National Institutes of Health this morning, I found a number of articles citing the link between SSRI drug use during pregnancy and the risk for adverse birth outcomes.  (For other articles I’ve written on the connection between SSRIs… Continue Reading

2010 – Risk for Atrial Septal Defect Dramatically Increased by Prenatal Paxil Exposure

Posted in Paxil Birth Defects, SSRI Birth Defects

An article published in the February, 2010 edition of the medical journal Birth Defects Research titled “First-trimester use of paroxetine and congenital heart defects: a population-based case-control study.” provides further evidence for the connection between paroxetine (Paxil) and cardiovascular birth defects. This study, conducted by M.K. Bakker et al., a Dutch research team, “performed a… Continue Reading

2010 – Infant suffers neonatal adaptation syndrome after gestational exposure to Paxil

Posted in Paxil Birth Defects, SSRI Birth Defects

An article by Laura Pogliani et al. (2010) titled “Paroxetine and neonatal withdrawal syndrome” published in BMJ Case Reports reports on a newborn who suffered neonatal withdrawal syndrome after prenatal exposure to paroxetine (Paxil). Here is the abstract of that article: “We report a case of neonatal withdrawal syndrome after in utero exposure to paroxetine… Continue Reading

2010 – Newborn twins require hospitalization after SSRI exposure

Posted in SSRI Birth Defects

In 2010, a team of Italian researchers led by Maria Marsella, from The University of Ferrara, published a case report in The Italian Journal of Pediatrics titled “Prenatal exposure to serotonin reuptake inhibitors: a case report”, shedding more light onto the link between selective serotonin reuptake inhibitors (SSRIs) and birth defects. The team writes “Two… Continue Reading

2011 – Depacon, SSRIs advised against during pregnancy citing defects and autism

Posted in Depacon / Depakene / Depakote, Paxil Birth Defects, SSRI Birth Defects

In recent years, a number of studies have demonstrated that Depacon (sodium valproate) use during pregnancy is linked to increased risk for a range of serious birth defects.  This epilepsy drug by Abbott Laboratories, Inc. is often safe, but has been linked to autism, neurological birth defects, heart defects, craniofacial birth defects, and a number… Continue Reading

2010 – Paxil, other SSRI drugs linked to serious birth defects

Posted in Paxil Birth Defects, SSRI Birth Defects

A French team of researchers led by S. Favrelière et al. published an article in L’Encephale titled “Treatment of depressed pregnant women by selective serotonin reuptake inhibitors: risk for the foetus and the newborn” in June, 2010 and provided further insights into the risks associated with selective serotonin reuptake inhibitor (SSRI) use during pregnancy posed… Continue Reading

Early pregnancy use of Prozac and Paxil linked to birth defects, “adverse perinatal outcome”

Posted in Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects

Over the past several decades, a number of studies have linked selective serotonin reuptake inhibitors (SSRIs) to a range of birth defects: neurological birth defects including spina bifida, cardiovascular birth defects including tricuspid atresia, craniofacial defects like cleft palate, developmental disorders such as autism, and neonatal adaptation disorders.  As the manufacturers of many SSRIs have… Continue Reading

2012 – American Family Physician: “Paroxetine Use Should Be Avoided During Pregnancy”

Posted in Paxil Birth Defects, SSRI Birth Defects

Published on April 15th, 2012, an important letter to the editor of American Family Physician was sent by Dr. Brian Budenholzer that cautioned against Paxil use during pregnancy.  (Accordingly, his piece was titled “Paroxetine Use Should Be Avoided During Pregnancy”.)  As it is relatively short, I have chosen to include it in its entirety below…. Continue Reading

2011 – Poor neonatal outcomes after SSRI exposure

Posted in SSRI Birth Defects

Published in the September, 2011 edition of Danish Medical Bulletin, an article by J. Fenger-Grøn et al. titled “Paediatric outcomes following intrauterine exposure to serotonin reuptake inhibitors: a systematic review.” “addresses the potential adverse effects on the foetus and child of maternal SRI medication.”  For clarity, “SRI” stands for serotonine reuptake inhibitors, and for our… Continue Reading

2014 – Paxil exposure dramatically raises risk for birth defects

Posted in Paxil Birth Defects, SSRI Birth Defects

An article published March 11, 2014 in BJOG: an international journal of obstetrics and gynaecology by L. Ban et al., a team from The University of Nottingham in the United Kingdom, titled “Maternal depression, antidepressant prescriptions, and congenital anomaly risk in offspring: a population-based cohort study.” provides insight into the connection between neonatal exposure to… Continue Reading

2011 – Scientists study how SSRIs cause heart defects

Posted in SSRI Birth Defects

A 2011 article published in that year’s December edition of the medical journal Reproductive Toxicology provides a bit of deeper insight into the connection between prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) and heart defects. In the article, titled “Selective serotonin reuptake inhibitors (SSRIs) and heart defects: potential mechanisms for the observed associations.”, T.W…. Continue Reading

Several studies link finasteride (Proscar, Propecia) to sexual dysfunction

Posted in Propecia / Proscar

Since the early 1990s, scientists and medical researchers have found that finasteride use is linked to sexual dysfunction in the form of erectile dysfunction, loss of libido, ejaculation disorder, and other ailments.  This chemical is the active chemical in the hair loss drug Propecia (finasteride 1mg) and the benign prostatic hyperplasia (BPH) drug, Proscar (finasteride… Continue Reading

Study shows that long-term sexual side effects of finasteride are linked to anxiety, depression

Posted in Propecia / Proscar

Here is an excerpt from a 2013 article appearing in Journal of Sexual Medicine titled “Neuroactive steroid levels are modified in cerebrospinal fluid and plasma of post-finasteride patients showing persistent sexual side effects and anxious/depressive symptomatology.”: “Observations performed in a subset of subjects treated with finasteride (an inhibitor of the enzyme 5α-reductase) for male pattern… Continue Reading

Another study links Proscar and Propecia to depression following sexual side effects

Posted in Propecia / Proscar

In the September 2012 edition of Journal of Clinical Psychiatry, medical researcher MS Irwig published a study titled “Depressive symptoms and suicidal thoughts among former users of finasteride with persistent sexual side effects.”, illustrating one dimension of the truly devastating effects of Propecia (finasteride 1mg, for hair loss) and Proscar (finasteride 5mg, for benign prostatic… Continue Reading

2012 – Study finds birth defects linked to prenatal Paxil, Prozac exposure

Posted in Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects

Published in the December, 2012 edition of Therapeutic Drug Monitoring, an article by H. Malm titled “Prenatal exposure to selective serotonin reuptake inhibitors and infant outcome.”  provides further insight into the connection between prenatal exposure to selective serotonin reuptake inhibitor (SSRI) drugs and adverse birth outcomes.  Malm has done a great deal of research on… Continue Reading

2011 – 32% of Metal-on-Metal Hip Replacement Patients Endure Pseudotumors

Posted in DePuy Hip Replacement

A 2011 article by D.H. Williams et al. published in that year’s December edition of Journal of Bone and Joint Surgery (US) titled “Prevalence of pseudotumor in asymptomatic patients after metal-on-metal hip arthroplasty.” sheds further important insight into the tendency for metal-on-metal hip replacements to release dangerous metal ions into the bloodstream. One result of… Continue Reading