A 2006 piece published in Neuroendocrinology Letters by M. Kopecek et al. titled “Low-dose risperidone augmentation of antidepressants or anxiolytics is associated with hyperprolactinemia.” states “Risperidone in antipsychotic doses induces hyperprolactinemia” and aims to “verify whether the same is true for low doses of risperidone (0.5-2 mg per day) added to antidepressants or anxiolytics.” That is, the study acknowledges that Risperdal (risperidone) is known to raise levels of prolactin – the hormone responsible for breast development and milk productions – and wanted to test if adding even a very small amount of the drug to a patient’s normal prescription of another antipsychotic would have the same effect. The condition characterized by dramatically-elevated prolactin levels is called “hyperprolactinemia”.
Admittedly, this was a small study, including only 12 patients who used risperidone “as an augmentation treatment to antidepressants (n=8), anxiolytics (n=6) and mood stabilizers (n=2)”. However, the results were clear: “11 of 12 patients had hyperprolactinemia.”
Researchers continue, stating a “Significant correlation between risperidone daily dose and plasma prolactin level … was detected” and “Two women suffered from galactorrhea and one from amenorrhea.” (hyperlinks added)
As such, researchers concluded that “Even low doses of risperidone used as an augmentation to antidepressants or benzodiazepines are associated with hyperprolactinemia and can induce endocrinological side effects”, stating that “The co-medication of antidepressants and benzodiazepines can potentially increase intensity of prolactinemia.”
Due to the fact that the manufacturer of Risperdal (risperidone) has failed time and again to adequately warn users of the risk for hyperprolactinemia and potential gynecomastia associated with Risperdal use, a number of Risperdal lawsuits have been filed. If you or a loved one used Risperdal and suffered these or other complications as a result, you too may be entitled to significant financial compensation for you undue injury and suffering. For a free, no-obligation case consultation, contact our team of Risperdal lawyers at the information provided below. We have the compassion, resources, and skills required to win the justice you deserve. Call today and see how we can help.
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Our Risperdal Lawsuit Information page is a great place to start if you have any questions about Risperdal.