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Dangerous Drugs & Medical Devices News & Commentary on Prescription Drug & Medical Device Lawsuits

Monthly Archives: January 2014

2005 – Study finds 92.3% of Risperdal patients suffer hyperprolactinemia

Posted in Risperdal

In 2005, a team of Polish researchers published a study titled “Prolactin secretion disturbances in schizophrenic patients treated with 2nd generation antipsychotics–risperidone and olanzapine” in Psychiatria Polska that aimed to further elucidate the connection between the use of second-generation antipsychotics and elevation of prolactin.  Prolactin is a hormone in the body responsible for breast development… Continue Reading

2006 – 11 of 12 Risperdal patients suffered hyperprolactinemia

Posted in Risperdal

A 2006 piece published in Neuroendocrinology Letters by M. Kopecek et al. titled “Low-dose risperidone augmentation of antidepressants or anxiolytics is associated with hyperprolactinemia.” states “Risperidone in antipsychotic doses induces hyperprolactinemia” and aims to “verify whether the same is true for low doses of risperidone (0.5-2 mg per day) added to antidepressants or anxiolytics.”  That… Continue Reading

2005 – Risperdal increases prolactin levels in children two-fold, adults eight-fold

Posted in Risperdal

In 2005, a team of researchers led by JA Hellings published a report titled “Risperidone-induced prolactin elevation in a prospective study of children, adolescents, and adults with mental retardation and pervasive developmental disorders.” that aimed to determine if Risperdal (risperidone) caused elevated prolactin levels in females more than males.  Elevated prolactin levels (hyperprolactinemia) may result… Continue Reading

2012 – Very high rate of pseudotumors seen with metal-on-metal hip replacements

Posted in DePuy Hip Replacement

In a 2012 study appearing in Clinical Orthopaedics and Related Research titled “Pseudotumors are common in well-positioned low-wearing metal-on-metal hips.”, AK Matthies et al. write “Pseudotumors are sterile inflammatory lesions found in the soft tissues surrounding metal-on-metal (MOM) and metal-on-polyethylene hip arthroplasties. In patients with MOM hip arthroplasties, pseudotumors are thought to represent an adverse… Continue Reading

2010 – Pseudotumors, high metal ion levels associated with metal-on-metal hip replacements

Posted in DePuy Hip Replacement

A 2010 article published in Journal of Orthopaedic Research by YM Kwon et al. titled “Lymphocyte proliferation responses in patients with pseudotumors following metal-on-metal hip resurfacing arthroplasty.” studied “the incidence and level of metal-induced systemic hypersensitivity in patients” who underwent metal-on-metal hip resurfacing arthroplasty (MoHRA), “both with and without pseudotumor by measuring lymphocyte proliferation responses… Continue Reading

2013 – Pseudotumors linked to metal-on-metal hip arthroplasty

Posted in DePuy Hip Replacement

In 2013, a paper published in Clinical Orthopaedics and Related Research titled “The natural history of inflammatory pseudotumors in asymptomatic patients after metal-on-metal hip arthroplasty.” by SA Almousa et al. provides background for itself, stating in part “Although pseudotumors have been reported in 32% of asymptomatic metal-on-metal hips, the natural history of asymptomatic pseudotumors is… Continue Reading

2013 – Many metal-on-metal hip replacement patients suffer adverse reactions to metal debris

Posted in DePuy Hip Replacement

An article appearing in the May, 2013 edition of Orthopedics titled “Prevalence of adverse reactions to metal debris following metal-on-metal THA.” by M. Hasegawa et al. lives up to its title and aimed to “determine the prevalence of adverse reactions to metal debris (ARMD) following large-diameter metal-on-metal total hip arthroplasty.” In recent years, a number… Continue Reading

Several Avenues for Healthcare Reform Outined

Posted in Politics

A recent article from Slate.com by Matthew Yglesias provides an interesting overview of problems and solutions in health care reform. Published Friday January 24th 2014, the report begins by citing a recent Gallup poll demonstrating a recent and dramatic decline in the number of Americans without health insurance.  Likely the result of the further implementation… Continue Reading

2007 – 66% and 76% of Patients Face LAP-BAND Complications

Posted in Allergan LAP-BAND

We are no longer accepting cases regarding these products.  Due to a terrible Supreme Court ruling, consumers injured by this product are no longer permitted to sue the manufacturers of this device.  We wish we could help, but the Supreme Court has taken the rights of citizens away to protect the profits of medical device… Continue Reading

2002 – LAP-BAND Reoperation Rate 35%

Posted in Allergan LAP-BAND

We are no longer accepting cases regarding these products.  Due to a terrible Supreme Court ruling, consumers injured by this product are no longer permitted to sue the manufacturers of this device.  We wish we could help, but the Supreme Court has taken the rights of citizens away to protect the profits of medical device… Continue Reading

2005 – 10% LAP-BAND Explantation Rate Seen in Teenagers

Posted in Allergan LAP-BAND

We are no longer accepting cases regarding these products.  Due to a terrible Supreme Court ruling, consumers injured by this product are no longer permitted to sue the manufacturers of this device.  We wish we could help, but the Supreme Court has taken the rights of citizens away to protect the profits of medical device… Continue Reading

2006 – 17% of Gastric Banding Patients Required Reoperation

Posted in Allergan LAP-BAND

We are no longer accepting cases regarding these products.  Due to a terrible Supreme Court ruling, consumers injured by this product are no longer permitted to sue the manufacturers of this device.  We wish we could help, but the Supreme Court has taken the rights of citizens away to protect the profits of medical device… Continue Reading

2006 – Causes for LAP-BAND reoperation detailed by study

Posted in Allergan LAP-BAND

We are no longer accepting cases regarding these products.  Due to a terrible Supreme Court ruling, consumers injured by this product are no longer permitted to sue the manufacturers of this device.  We wish we could help, but the Supreme Court has taken the rights of citizens away to protect the profits of medical device… Continue Reading

FDA Exerts New Authority over Compounding Pharmacies with Drug Quality and Security Act

Posted in FDA Regulation, Politics, Public Health

In the wake of the recent fungal meningitis outbreak that left 64 dead and infected some 751 Americans, traced back contaminated steroid injections from the New England Compounding Center (Framingham, MA), the United States Food and Drug Administration has sought greater oversight over the pharmacy compounding industry. To that end, Congress passed the Drug Quality… Continue Reading

2006 – LAP-BAND has worse outcomes than gastric bypass

Posted in Allergan LAP-BAND

We are no longer accepting cases regarding these products.  Due to a terrible Supreme Court ruling, consumers injured by this product are no longer permitted to sue the manufacturers of this device.  We wish we could help, but the Supreme Court has taken the rights of citizens away to protect the profits of medical device… Continue Reading

2008 – Study shows smaller metal-on-metal hip replacements cause smaller increase in blood metal ion levels

Posted in DePuy Hip Replacement

In a 2008 article published by J. Antoniou et al. in The Journal of Bone and Joint Surgery titled “Metal ion levels in the blood of patients after hip resurfacing: a comparison between twenty-eight and thirty-six-millimeter-head metal-on-metal prostheses.”, the authors write “Metal ion toxicity, metal hypersensitivity, and metal carcinogenicity are causes for concern for patients… Continue Reading

2011 – Metal ion levels “significantly higher” in metal-on-metal hip replacements at 24 months

Posted in DePuy Hip Replacement

In a 2011 report by JM Smolders et al. published in Acta Orthopaedica titled “Metal ion levels and functional results after either resurfacing hip arthroplasty or conventional metal-on-metal hip arthroplasty.”, a team of medical researchers aimed to determine whether larger cup sizes in metal-on-metal hip replacements led to higher levels of metal ions in the… Continue Reading

2005 – Elevated prolactin levels found in 68% of youth Risperdal users

Posted in Risperdal

In 2005, a report by JR Stevens et al. published in Journal of Child and Adolescent Psychopharmacology and titled “Elevated prolactin levels in male youths treated with risperidone and quetiapine.” aimed to determine the extent to which Risperdal (risperidone) and Seroquel (quetiapine) raised levels of prolactin in patients.  Prolactin is the hormone responsible for breast… Continue Reading

2001 – Study shows Risperdal caused 28% of children to have elevated prolactin levels

Posted in Risperdal

A 2001 paper by G. Masi et al. published in Journal of Child and Adolescent Pharmacology begins its abstract as follows: “Although hyperprolactinemia is a common side effect during risperidone treatment in adult patients, no information is available on young children.” To be clear, hyperprolactinemia is a condition characterized by elevated blood levels of prolactin,… Continue Reading