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Dangerous Drugs & Medical Devices News & Commentary on Prescription Drug & Medical Device Lawsuits

Monthly Archives: September 2013

2005 – Study shows SSRIs pose danger to developing fetus

Posted in SSRI Birth Defects

The objective of a study titled “Risks Associated with Selective Serotonin Reuptake Inhibitors in Pregnancy”, done by researchers from the Teratology Information Service, HUSLAB, at Helsinki University Central Hospital in Finland, was to determine the effects of selective serotonin reuptake inhibitors (SSRIs) on pregnancy outcomes; and implicitly, to determine the likelihood that children whose mothers… Continue Reading

2006 – Danger posed to developing babies by SSRIs

Posted in SSRI Birth Defects

Back in 2006, there was still relatively little information about the fetus-damaging capabilities of selective serotonin reuptake inhibitors (SSRIs).  The objective of a study published that year by a team from the Department of Clinical Epidemiology at Aarhus University Hospital, in Aarhus, Denmark, titled “Maternal Use of Selective Serotonin Reuptake Inhibitors and Risk of Congenital… Continue Reading

2010 – Paxil associated with a number of dangerous birth defects

Posted in Paxil Birth Defects, SSRI Birth Defects

Selective serotonin reuptake inhibitors (SSRIs) are serious medications that help with depression and anxiety disorders.  These disorders are the most prevalent mental health disorders in the United States and it is estimated that over 40 million Americans suffer from some type of mental health problems.  Medications can affect each individual differently.  Biological factors, such as… Continue Reading

2004 – SSRIs connected with serious birth defects

Posted in SSRI Birth Defects

Selective serotonin reuptake inhibitor (SSRI) antidepressants and benzodiazepines are common medications used for the treatment of anxiety disorders and depression during pregnancy.  An increased risk for neonatal discontinuation and prenatal SSRI exposure has been shown in some studies.  The objective of a study done by the Department of Pediatrics, Centre for Community Child Health Research,… Continue Reading

2007 – Paxil associated with serious birth defects

Posted in Paxil Birth Defects, SSRI Birth Defects

Depression and anxiety plague over 40 million Americans in the United States, leading these to be the most common mental illness in America.  There are some risks associated with all medications, and some studies suggest that selective serotonin reuptake inhibitor drugs (SSRIs) have the ability to cause harm or damage to a developing fetus or… Continue Reading

Paxil, other SSRIs found to have link to birth defects

Posted in Paxil Birth Defects, SSRI Birth Defects

RL David, from the Center for Health Studies, Group Health Cooperative, in Seattle, WA, conducted a study called “Risks of Congenital Malformations and Perinatal Events Amoung Infants Exposed to Antidepressant Medications During Pregnancy”.  The purpose of this study was to determine the risks involved with perinatal complications and congenital defects among offspring exposed to antidepressants… Continue Reading

2013 – Study shows: SSRIs linked to birth defects

Posted in SSRI Birth Defects

Anxiety, depression and other related disorders affect over 40 million Americans, leading these disorders to be the most common mental illness in the U.S.  The purpose of a study titled “Use of Selective Serotonin Reuptake Inhibitors in Pregnancy and Cardiac Malformations: a Propensity-Score matched Cohort in CPRD”, written by the US Food and Drug Administration,… Continue Reading

Paxil found to be associated with birth defects

Posted in Paxil Birth Defects, SSRI Birth Defects

Selective Serotonin Reuptake Inhibitors (SSRIs) are compounds used as antidepressants.  They are used in the treatment of anxiety disorders, depression, and some personality disorders.  SSRIs are psychotropic drugs discovered through a process the medical world calls rational drug design.  The basics of rational drug design are finding molecules that affect specific biological targets.    Psychotropic drugs… Continue Reading

Depacon, other AEDs found associated with severe congenital malformations

Posted in Depacon / Depakene / Depakote

In 1981, medical researcher F. Majewski, published a study in the Internaltional Journal of Biological Research in Pregnancy titled “The teratogenicity of Hydantoins and Barbiturates in Humans, With Considerations on the Etiology of Malformations and Cerebral Disturbances in the Children of Epileptic Parent”. The study consisted of 194 children from epileptic mothers and 71 children… Continue Reading

1996 – Risk AEDs pose to developing fetus evaluated

Posted in Depacon / Depakene / Depakote

The objectives of a 1996 study done by The Medical Birth Registry of Norway at University of Bergen, in Norway, titled “Spina Bifida and Cleft Lip Among Newborns of Norwegian Women With Epilepsy: Changes Related to the Use of Anticonvulsants”, were to determine the association between the use of anticonvulsants for epileptic women during or… Continue Reading

FDA Recall Safety Alert: Siemens MicroScan Synergies plus® and MicroScan® rapID/S plus Negative Panels

Posted in Recalls, Safety Alerts

On August 21st, the US Food and Drug Administration issued a Class-1 recall for Siemens MicroScan Synergies plus® and MicroScan® rapID/S plus Negative Panels, affecting “78,020 panels distributed in the US between 07/11/2011 and 08/02/2013.” (FDA) These panels come as part of kits used by medical professionals to test a patient’s saliva or tissue for… Continue Reading

“Neurologic Care of Pregnant Women with Epilepsy”: AEDs dangerous for fetus

Posted in Depacon / Depakene / Depakote

One common neurologic condition seen in women who are of child-bearing age is epilepsy.  There are many concerns child bearing age women with epilepsy have when it comes to having a safe and healthy pregnancy, however most epileptic women will have a safe pregnancy and carry to term a healthy child.  Author Zahn C., from… Continue Reading

2007 – Connection found between AED use and birth defects

Posted in Depacon / Depakene / Depakote

There is an increased risk that children exposed to antiepileptic drugs in utero will develop major congenital malformations.  Despite these elevated risks, the majority of children exposed to antiepileptic drugs during development will be born free of any abnormal functional neurodevelopment.  Author Meador KJ, from the department of Neurology, Georgetown University Hospital, wrote an article… Continue Reading

Risk for birth defects “2-3 times greater” with in utero exposure to AEDs

Posted in Depacon / Depakene / Depakote

An article titled “The European Registry of Antiepileptic Drugs and Pregnancy”, from the Department of Experimental Neurology, University of Berlin, by Kretz R., et al., states that “All old-generation antiepileptic drugs (AEDs) are considered to be teratogenic. In Germany, one out of 200 pregnant women (0.5%) is treated with AEDs for epilepsy. The risk of… Continue Reading

1992 – Early explorations of the danger AEDs pose to developing babies

Posted in Depacon / Depakene / Depakote

A study done by a team from The Department of Neurology at St. Martino Hospital, in Genoa, Italy, titled “Epilepsy, Pregnancy, and Major Birth Anomalies: an Italian Prospective, Controlled Study”, followed 138 pregnancies, 97 women with epilepsy, and 88 women without epilepsy.  The women were matched for age during 140 pregnancies, and the study evaluated… Continue Reading

2010 – VPA (Depacon) Associated with 14 Congenital Malformations

Posted in Depacon / Depakene / Depakote

Some  studies suggest that the use of certain antiepileptic medications such as valproic acid (Depacon / Depakene / Depakote) in the first trimester is associated with an increased risk of spina bifida.  Limited information is available on the risks of other congenital malformations.  A study done by a team from the Department of Pharmacoepidemiology and… Continue Reading

2007 – Depacon, other AEDs demonstrated to be dangerous for fetus

Posted in Depacon / Depakene / Depakote

There is a clear understanding of the  harmful effects that antiepileptic drugs (AEDs) can have on a developing fetus or embryo; the medical community is pretty much done debating, and it is widely-accepted in medical literature that exposure to AEDs during development increases the risk of major congenital malformations (MCMs) in the fetus.  Some of… Continue Reading

1992 – Research shows danger of VPA therapy during pregnancy

Posted in Depacon / Depakene / Depakote

Around 90 percent of all epileptic women who are on antiepileptic drugs will bear children healthy children with no congenital malformations.  However, antiepileptic drugs do have the ability to cause harm to a developing fetus or embryo and congenital malformations are seen in a higher rate with women exposed to these drugs than is seen… Continue Reading

1991 – UK study shows AEDs increase risk for birth defects

Posted in Depacon / Depakene / Depakote

There are many risks involved with antiepileptic drugs and women of child-bearing age.  Dangerous pregnancies, interference with contraception, and major congenital malformations in the offspring are all factors associated with pregnant epileptics and AEDs.  These adverse effects seen from AEDs are a necessary risk due to the fact that seizures during pregnancy may cause harm… Continue Reading

Study shows: Certain kinds of TVM more dangerous than others

Posted in Vaginal Mesh

Pelvic organ prolapse is a common condition among aging women, characterized by the shifting of pelvic organs, which push up against the vaginal walls.  The condition may occur as a result of surgery or childbirth and oftentimes causes pain or discomfort.  One method of treating prolapse is to use a synthetic polypropylene mesh to provide… Continue Reading

Many women require re-operation after TVM use

Posted in Vaginal Mesh

Transvaginal mesh (TVM) is a fairly new mesh-augmented suspension system, only becoming commercially available in 2004.  Early studies reported a promising short-term anatomical success rate of 94%.  Further studies were deemed necessary after the Food and Drug Administration reported several adverse outcomes associated with the use of these mesh kits. One such study, titled “Two-Year… Continue Reading

2013 – Study shows some vaginal mesh effective but risky

Posted in Vaginal Mesh

Several studies have been conducted, evaluating the effectiveness of transvaginal mesh (TVM) usage in treating damaged vaginal tissues.  Initial studies primarily focused on the anatomical success of TVM, with less emphasis on functional outcome.  Dr. Salil Khandwala conducted a study titled “Transvaginal Mesh Surgery for Pelvic Organ Prolapse: One-Year Outcome Analysis,” published in the journal… Continue Reading