In 2009, Marco Tuccori, PharroD, et al. published a report titled “Safety Concerns Associated With the Use of Serotonin Reuptake Inhibitors and Other Serotonergic/Noradrenergic Antidepressants During Pregnancy: A Review” in Clinical Therapeutics that establishes reason to believe certain SSRI medications are unsafe for a developing fetus.
Once proper consent was obtained, the Tuccori et al. team reviewed several large patient records databases to determine if an association could be made between prenatal exposure to SSRI drugs and an increased incidence of major congenital malformations. After statistical analyses were performed, Tuccori and his colleagues concluded that “The available evidence suggests that SSRIs and other serotonergiclnoradrenergic antidepressants should be used with caution during pregnancy, with careful follow-up of infants exposed to these agents in utero.”
Tuccori and his team found that SSRI drugs were associated with a variety of congenital malformations, particularly malformations of the heart. The main birth defect found to be significantly associated with maternal use of SSRI drugs (particularly Paxil) was persistent pulmonary hypertension of the newborn, though other studies have shown significant associations between Paxil and a number of other serious congenital malformations.
Due to the fact that many women weren’t made aware of the relationship between Paxil and birth defects during pregnancy by the boxed warning on Paxil medication, a number of Paxil birth defects lawsuits have been filed.
If you or a loved one used Paxil during pregnancy and gave birth to a child with a congenital malformation, please do not hesitate to contact our team of Paxil lawyers.
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