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Dangerous Drugs & Medical Devices News & Commentary on Prescription Drug & Medical Device Lawsuits

Monthly Archives: July 2013

Depacon Dosage Important in Risk for Birth Defects

Posted in Depacon / Depakene / Depakote

Depacon (vallproic acid) is an antiepileptic drug used to treat a wide range of seizure disorders.  There are many benefits that patients receive from certain antiepileptic drugs.  However these drugs (AEDs) don’t go without certain side effects.  Some common side effects from AEDs are migraine headaches, dizziness, nausea, vomiting, sleepiness, weakness, change in taste, numbness… Continue Reading

Study Shows: Vaginal Mesh Also Unsafe for UI Surgery

Posted in Vaginal Mesh

Urinary incontinence plagues people all over the world, leading to experiences of discomfort and stress.  Midurethral mesh slings are now the most popular method for surgically alleviating urinary incontinence.  These mesh slings are the very same synthetic meshes that are used in pelvic floor reconstruction following pelvic organ prolapse.  In recent years, the difference between… Continue Reading

2013 – Transvaginal mesh widely considered unsafe

Posted in Vaginal Mesh

Because nearly one tenth of all women worldwide experience pelvic organ prolapse (POP) during their lives, many top medical professionals today strive to develop treatment more reliable than transvaginal mesh (TVM), a treatment option associated with a high rate of failure and complications of vaginal mesh. A current study titled, “Indications, Contraindications, and Complications of… Continue Reading

Complications of TVM erosion

Posted in Vaginal Mesh

The use of transvaginal mesh kits in pelvic floor reconstruction surgery has begun to be questioned clinically as the number of cases of complications and adverse effects has steadily risen.  The  complications can lead to pain for not only the patient but for their significant others during intercourse, often times leading patients to require further… Continue Reading

Additional surgery required to remove ineffective TVM

Posted in Vaginal Mesh

Currently, synthetic mesh kits are being more commonly used in reparatory surgery for prolapsed pelvic organs.  However, as stated by Lawrence Lin, et. al., in a recent article titled, “Dyspareunia and Chronic Pelvic Pain after Polypropylene Mesh Augmentation for Transvaginal Repair of Anterior Vaginal Wall Prolapse,” there seems to be no clinical research on the… Continue Reading

Severe complications associated with transvaginal mesh

Posted in Vaginal Mesh

The use of transvaginal mesh kits has grown substantially in recent years as new products are being designed constantly.  However, numerous transvaginal mesh lawsuits have emerged because of the inconsistent success rates offered by the field of different transvaginal mesh products.  Lawsuits have not only emerged because of unsuccessful procedures involving transvaginal mesh kits, but… Continue Reading

2003: “Management of vaginal erosion of polypropylene mesh slings”

Posted in Vaginal Mesh

With the current controversy surrounding the use of transvaginal mesh kits for the reparatory surgery of prolapsed pelvic organs, alternatives methods are constantly being explored.  Recently, polypropylene slings have been used instead of more traditional transvaginal mesh kits using other synthetic bases for their designs, utilizing a tension-free sling that is aimed at causing fewer… Continue Reading

Effects of TVM on Sexual Function

Posted in Vaginal Mesh

The use of transvaginal mesh in the surgical repair of pelvic organ prolapse has recently led to a large number of transvaginal mesh lawsuits as a result of the inconsistent success rates and the numerous complications associated with these methods.  The controversy has mainly stemmed from the lack of clinical research done to prove the… Continue Reading

New AEDs Safer than Depacon in Pregnancy

Posted in Depacon / Depakene / Depakote

In 2004, a study published in Epilepsy & Behavior demonstrated that the new generation of antiepileptic drugs (AEDs) pose less danger to a developing fetus than do older drugs. This study comes from an Argentinian research team led by Meischenguiser et al. who studied two different groups of children: one group of children whose mothers… Continue Reading

2009 – Depacon, other AEDs pose danger to fetus

Posted in Depacon / Depakene / Depakote

A 2009 article in Epilepsiai showed clearly that “adverse pregnancy and birth outcome in women with epilepsy is mainly confined to AED-exposed pregnancies.”  This article, by G. Veiby et al., reviewed records from “the compulsory Medical Birth Registry of Norway, [and] all 2,861 deliveries by women with epilepsy recorded from 1999-2005 were compared to all… Continue Reading

1998 – Depacon, other AEDs associated with life-threatening birth defects

Posted in Depacon / Depakene / Depakote

In 1998, a report published Annals of Pharmacotherapy by DP Lewis et al. aimed to illustrate the importance of folic acid during pregnancy, and as antiepileptic drugs (AEDs) lower serum folic acid levels, this report also illustrates that AEDs can be dangerous for a developing fetus.   The main ingredient in most AEDs used today is… Continue Reading

1992 – Research Warns: Depacon Dangerous in Pregnancy

Posted in Depacon / Depakene / Depakote

In 1992, medical researchers AV Delagdo-Escueta and D Janz reported that “All women with epilepsy who are of childbearing age should be advised (preferably before conception) that the incidence of malformations in infants of mothers with epilepsy who are treated with antiepileptic drugs (AEDs) is two or three times that of infants of mothers without… Continue Reading

SSRIs increase risk for low birth weight, preterm birth, fetal death

Posted in SSRI Birth Defects

Published in 2006, a paper by Shi Wu Wen, MB, PhD, et al. titled “Selective serotonin reuptake inhibitors and adverse pregnancy outcomes” published in The American Journal of Obstetrics and Gynecology aimed “to assess the safety of the use of selective serotonin reuptake inhibitors in pregnancy.” The Wen et al. (2006) study group included “972… Continue Reading

Effexor, other SSRIs associated with serious congenital malformations

Posted in Effexor Birth Defects, SSRI Birth Defects

In 2004, research by F. Yaris et al. published in Reproductive Toxicology evaluated the safety of newer antidepressants in pregnancy. To-date, a number of antidepressant drugs, especially SSRIs (Paxil, Prozac, Celexa, Effexor, others) have been associated with a range of life-threatening birth defects. More information on SSRI and birth defects. This Yaris et al. (2004)… Continue Reading

Cipro tied to retinal detachment

Posted in Cipro

In an article published last year in The Journal of The American Medical Academy, by Mahyar Etminan et al. set out to “examine the association between use of oral fluoroquinolones and the risk of developing a retinal detachment.”  Oral fluoroquinolones (Cipro, others) are antibiotics used in a wide range of medical procedures, and have recently… Continue Reading

Levetiracetam a better option than sodium valproate (Depacon) in pregnancy

Posted in Depacon / Depakene / Depakote

In 2011, R. Shallcross et al. published a report in Neurology that compared the safety of two antiepileptic drugs, levetiracetam and sodium valproate (Depacon Depakene, Depakote, others), for a developing fetus.  Shallcross et al. (2011) compared the health of 51 children that had been exposed to levetiracetam while in the womb to 44 children that… Continue Reading

Depacon Linked to Increased Risk for Autism

Posted in Depacon / Depakene / Depakote

In April of this year, Journal of the American Medical Association published a case-controlled study, by Jakob Christensen, PhD et al., showing a clear association between prenatal sodium valproate (Depacon, Depakene, Depakote) exposure and increased risk of autism spectrum disorder and childhood autism. Sodium valproate (also “valproic acid,” “divalproex sodium”) is the main ingredient in… Continue Reading

Depacon / Depakene / Depakote Linked to Serious Birth Defects

Posted in Depacon / Depakene / Depakote

A recent article published in The Journal of Research in Medical Sciences by Lelia Etemad et al. (2012) reviews the safety of prenatal exposure to antiepileptic drugs (AEDs).  With epilepsy affecting about 2.2 million Americans, this is a problem that must not be overlooked. Though, states Etemad (2012), “the majority of children born to women… Continue Reading

Ciprofloxacin (Cipro) linked to increased risk of retinal detachment

Posted in Cipro

Published earlier this year in The Journal of the American Medical Association, a piece by Dr. Dennis P. Han et al. concludes that “patients taking oral fluoroquinolones were at a higher risk of developing a retinal detachment compared with nonusers, although the absolute risk for this condition was small.”  Oral fluoroquinolones, such as ciprofloxacin (Cipro),… Continue Reading

Study Shows: Paxil Associated with Increased Risk for PPHN

Posted in Paxil Birth Defects, SSRI Birth Defects

In 2009, Marco Tuccori, PharroD, et al. published a report titled “Safety Concerns Associated With the Use of Serotonin Reuptake Inhibitors and Other Serotonergic/Noradrenergic Antidepressants During Pregnancy: A Review” in Clinical Therapeutics that establishes reason to believe certain SSRI medications are unsafe for a developing fetus. Once proper consent was obtained, the Tuccori et al…. Continue Reading

Effexor, Paxil Associated with Fetal Heart Malformation

Posted in Effexor Birth Defects, Paxil Birth Defects, SSRI Birth Defects

A 2007 review published in Pharmacotherapy analyzed the effects of several common antidepressant medications during pregnancy and concluded that “Third-trimester exposure to newer antidepressants, including SSRIs and serotonin-norepinephrine reuptake inhibitors (e.g., venlafaxine), has been associated with a poor neonatal adaptation syndrome. In addition, SSRI use may be associated with an increased risk of persistent pulmonary… Continue Reading

Medtronic’s SynchroMed Infusion Pumps Recalled

Posted in Devices, SynchroMed Infusion Pumps

It has been recently brought to public attention that the SynchroMed infusion pumps produced by Medtronic Inc. have been found to have serious flaws that have led to massive recalls.  The U.S. Food and Drug Administration (FDA) issued a Class I recall on the Medtronic SyncrhoMed infusion pumps.  The SynchroMed infusion pumps were originally designed… Continue Reading

SynchroMed Infusion Pumps Recalled by FDA

Posted in Devices, Recalls, SynchroMed Infusion Pumps

In a current announcement recorded in the Star Tribune, Medtronic, Inc. reported that 14 total patient deaths have occurred in connection to their SynchroMed infusion pumps.  The deaths have been reported as occurring between spring of 1996 and spring of 2013.  The article reports that just one day prior to the public announcement from Medtronic, the… Continue Reading