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Dangerous Drugs & Medical Devices News & Commentary on Prescription Drug & Medical Device Lawsuits

Monthly Archives: June 2013

Metal Toxicity and Metal-on-Metal Hip Replcement

Posted in DePuy Hip Replacement, Stryker Hip Replacement

Metal-on-metal bearings in hip resurfacing arthroplasty have been associated with prolonged periods of elevated metal ion circulation in the bloodstream.  Specific ions, such as chromium and cobalt are known to be particularly threatening to the general health of the patient, often times leading to symptoms associated with metal toxicity.  A recent study focused on the… Continue Reading

Danger of Metal-on-Metal Hip Replacements

Posted in DePuy Hip Replacement, Stryker Hip Replacement

Metal-on-metal (MOM) total hip replacement has been a commonly used approach to hip repair, and with this surgery the risk of adverse effects is always present.  These effects include osteolysis, or bone-decay, as well as toxicity due to the metals that release ions into the body.  Recently, ceramic-on-ceramic total hip replacement surgery has been considered… Continue Reading

Negative Side-Effects of Transvaginal Mesh

Posted in Vaginal Mesh

Transvaginal mesh repair is commonly used for the repair of anterior vaginal wall prolapse.  Some reports have observed that overactive bladder symptoms are occasionally improved due to the use of transvaginal mesh in the repair of vaginal wall prolapse.  A study conducted by Cheng-Yu Long, et. al. focused on the possible positive side effects caused… Continue Reading

Adverse Health Events Related to Metal-on-Metal Hip Replacements

Posted in DePuy Hip Replacement, Stryker Hip Replacement

Metal-on-metal hip replacement (MOM) was introduced in total hip replacement to avoid complications such as osteolysis, the process where bone marrow is not produced, causing weakness in joints and bone structure to occur, a phenomenon often times found in patients with conventional ultra-high molecular weight polyethylene bearings.  This ailment is oftentimes only symptomatic in giving… Continue Reading

Certain angle ratios of metal-on-metal hip replacements related to high levels of metal ions in the blood

Posted in DePuy Hip Replacement, Stryker Hip Replacement

Many factors affect the blood metal ion levels of patients after metal-on-metal hip arthroplasty.  While certain ions have found to cause a range of adverse events, others, such as chromium and cobalt have been found to be carcinogenic.  A current study by AlisterJ. Hart et al. focused on the main surgically-adjustable variable, the amount of… Continue Reading

Dangers of Chromium and Cobalt Ion Exposure in Metal-on-Metal Hip Replacement

Posted in DePuy Hip Replacement, Stryker Hip Replacement

A recent study conducted by Wolf-Christoph Witzleb et al. focused on the implications of the metal ions released through the expected corrosion that occurs after a metal-on-metal hip replacement or hip resurfacing.  Two of these metal ions, cobalt and chromium are known to have carcinogenic and mutagenic effects in patients with metal-on-metal hips, leading to… Continue Reading

High Levels of Dangerous Metal Ions in Blood after Metal-on-Metal Hip Replacement

Posted in DePuy Hip Replacement, Stryker Hip Replacement

A recent study conducted by Wolf-Christoph Witzleb et al. focused on the implications of the metal ions released through the expected corrosion that occurs after a metal-on-metal hip replacement or hip resurfacing.  Two of these metal ions, cobalt and chromium are known to have carcinogenic and mutagenic effects in patients with metal-on-metal hips, leading to… Continue Reading

Study Shows Complications of Transvaginal Mesh

Posted in Vaginal Mesh

A recent study published in The American Journal of Obstetrics and Gynecology indicated that while the Posterior IVS Tunneller transvaginal mesh delivery system was the first of its kind, and was a viable option for pelvic organ prolapse repair, a range of similar systems were released soon after without being subjected to clinical trials.  All… Continue Reading

Kidney Damage as a Result of Metal-on-Metal Hip Replacement

Posted in DePuy Hip Replacement, Stryker Hip Replacement

A recent study in Symposium posed the question of whether metal ions released from arthroplasty reach levels comparable to that of workers in heavy metal industries.  The metal ions are most commonly cleared through urine, meaning that high enough levels can lead to renal damage.  The study, published by Dr. Massimo Corradi et al. (2011),… Continue Reading

Risk-Benefit Analysis of Transvaginal Mesh

Posted in Vaginal Mesh

With the rising use of transvaginal mesh in the treatment of anterior vaginal wall prolapse, studies are being done as to determine the benefits and risks of these new procedures.  Current studies aim at determining if there is any significant increase in the success rate of surgical vaginal wall repair due to the use of… Continue Reading