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Category Archives: Zoloft Birth Defects

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Prozac, Pazil, Zoloft, Celexa linked to Persistent Pulmonary Hypertension of the Newborn (PPHN)

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

Titled “Further findings linking SSRIs during pregnancy and persistent pulmonary hypertension of the newborn: clinical implications.”, this article appearing in the October, 2012 edition of CNS Drugs by M. Galbally et al., identifies persistent pulmonary hypertension of the newborn (PPHN) as a potential consequence of SSRI exposure before birth. Galbally et al. (2012) writes “Persistent… Continue Reading

2012 – Range of poor neonatal outcomes linked to SSRIs in pregnancy

Posted in Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

Over the past several decades, drugs like Prozac and Zoloft have come under fire over a connection to birth defects (and host of other negative consequences related to SSRI use in pregnancy).  Recently, I came across a piece by L.E. Grzeskowiak et al. (2012) published in Journal of Clinical Psychopharmacology titled “Neonatal outcomes after late-gestation… Continue Reading

If trace Zoloft in the water supply can hurt tadpoles, how do you think it affects your baby when you eat it?

Posted in SSRI Birth Defects, Zoloft Birth Defects

Titled “Growth and development of tadpoles (Xenopus laevis) exposed to selective serotonin reuptake inhibitors, fluoxetine and sertraline, throughout metamorphosis.,” an article by D.E. Conners and a team from The Department of Environmental Health Science at University of Georgia has demonstrated that Prozac and Zoloft in the water supply can inhibit the development of tadpoles.  While… Continue Reading

2009 – More research links SSRIs with birth defects: heart defects, adverse birth outcomes

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

In 2009, S. Alwan and J.M. Friedman, a research duo from the University of British Columbia in Vancouver, published a study titled “Safety of selective serotonin reuptake inhibitors in pregnancy.” in CNS Drugs that provided important insight into the link between gestational exposure to selective serotonin reuptake inhibitor drugs (such as Prozac, Paxil, and Zoloft)… Continue Reading

Study finds Zoloft exposure linked to heart defects

Posted in SSRI Birth Defects, Zoloft Birth Defects

Today, I found an article published in a 2013 edition of Pediatric Research by S.E. Haskell et al. (a team from University of Iowa Carver College of Medicine) titled “Sertraline exposure leads to small left heart syndrome in adult mice.” that further elucidates the connection between gestational Zoloft exposure and adverse birth outcomes. Haskell writes,… Continue Reading

Zoloft linked to poor neonatal adaptation

Posted in SSRI Birth Defects, Zoloft Birth Defects

The June, 2004 edition of Journal of Perinatology presented a study titled “Transient neonatal jitteriness due to maternal use of sertraline (Zoloft).” by R.P. Santos et al., providing important insight into the link between Zoloft expousre during pregnancy and adverse birth outcomes.  Here is the abstract of that article: “We describe the occurrence of marked… Continue Reading

1992 – Zoloft, SSRIs linked to craniofacial birth defects

Posted in SSRI Birth Defects, Zoloft Birth Defects

Searching the phrase “sertraline malformation” in PubMed, an online medical literature database curated by the US National Library of Medicine and National Institutes of Health, this morning I came across an article titled “Serotonin as a regulator of craniofacial morphogenesis: site specific malformations following exposure to serotonin uptake inhibitors.” by D.L. Shuey et al., appearing… Continue Reading

2009 – Research shows SSRIs cross placenta

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

Published in May, 2009 in Pharmacopsychiatry by a team of Australian researchers led by J. Rampono, an article titled “Placental transfer of SSRI and SNRI antidepressants and effects on the neonate.” provides further evidence that drugs such as Celexa, Lexapro, Prozac, Paxil, Zoloft, Effexor and others may cross the placenta and affect a developing fetus…. Continue Reading

Three more studies link Celexa, SSRIs to adverse birth outcomes

Posted in Celexa Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

Over the past several decades, a number of studies have linked Celexa exposure and birth defects.  This morning, I found several more, some of which are summarized below.  For more articles demonstrating the connection between birth defects and Celexa, follow the preceding link. In a 2013 edition of Fetal and Pediatric Pathology, an article by… Continue Reading

2012 – SSRIs associated with spontaneous abortion

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

Studies have shown that women suffering from depression during pregnancy can put the child at risk of developing malformations.  As such, selective serotonin reuptake inhibitors (SSRIs) are most commonly prescribed to the mother to avoid such complications.  Unfortunately, using these drugs during pregnancy may also put the child at risk of malformations.  To date, the… Continue Reading

2006 – Neonatal Abstinence Syndrome Seen in Children Exposed to SSRIs in Pregnancy

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

The objective of a study titled “Neonatal Abstinence Syndrome After in Utero Exposure to Selective Serotonin Reuptake inhibitors in Term Infants”, written by researchers from the Neonatal Intensive Care Unit at Schneider Children’s Medical Center of Israel, led by R. Levinson-Castiel was to determine the prevalence and clinical characteristics of neonatal abstinence syndrome in neonates… Continue Reading

2009 – Zoloft use during pregnancy raises risk for septal heart defects 3-fold

Posted in SSRI Birth Defects, Zoloft Birth Defects

The objective of a study done titled “Selective serotonin reuptake inhibitors in pregnancy and congenital malformations: population based cohort study” by  LH. Pedersen from the Department of Epidemiology, Institute of Public Health, Aarhus University, was to take a closer look between selective serotonin reuptake inhibitors taken during pregnancy and their ability to cause major congenital… Continue Reading

Maternal use of Effexor, other SSRIs may result in neonatal abstinence syndrome

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

A study conducted by the Department of Psychological Medicine, King Edward Memorial Hospital for Women, Subiaco, Australia, titled “Placental Transfer of SSRI and SNRI Antidepressants and Effects On The Neonate”, investigated placental transfer and neurobehavioural effects in neonates exposed to venlafaxine (Effexor), sertraline (Zoloft), paroxetine (Paxil), fluvoxamine, fluoxetine (Prozac), escitalopram, and citalopram (Celexa).  The neonates… Continue Reading

2004 – Doctors Avoid SSRIs in Pregnant Women

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

The objective of a study published by researchers from the OMNI Research Group within the Department of Obstetrics and Gynaecology at The University of Ottawa, in Ottawa ON, titled “The Use of Selective Serotonin Reuptake Inhibitors in Pregnancy”, was to update literature on the safety of using selective serotonin reuptake inhibitors during pregnancy. For this… Continue Reading

2005 – Research Shows Paxil, Prozac Triple Risk for Neonatal Behavioral Syndrome

Posted in Misc. Drugs, Paxil Birth Defects, Prozac Birth Defects, Zoloft Birth Defects

Published in a 2005 edition of the Journal of the American Medical Association, a study by Dr. Eydie L. Moses-Kolko et al., titled “Neonatal Signs After Late In Utero Exposure to Serotonin Reuptake Inhibitors,” reviews the danger posed to infants whose mothers used serotonin reuptake inhibitors (SRIs), a new type of antidepressant and anti-anxiety medication…. Continue Reading

Zoloft, Paxil, other SSRIs May Cause Birth Defects

Posted in Misc. Drugs, Paxil Birth Defects, Prozac Birth Defects, Zoloft Birth Defects

A 2006 study from Denmark, published in the medical journal Epidemiology, has evaluated the risk for birth defects and other neonatal complications that results from maternal use of SSRI drugs during pregnancy.  “SSRI” stands for selective serotonin reuptake inhibitor and represents a new class of antidepressant drugs that change levels of serotonin in the brain. … Continue Reading

Spina Bifida Linked to SSRI Use

Posted in Misc. Drugs, Paxil Birth Defects, Prozac Birth Defects, Zoloft Birth Defects

Spina Bifida (“myelomeningocele” being the most common form) is a birth defect in the larger class of “neural tube defects,” characterized by the malformation or underdevelopment of the neural tube in a developing infant before birth.  In spina bifida, “the backbone and spinal canal do not close before birth”[1] as they normally would. PubMed Health,… Continue Reading

Increased Risk of Anal Atresia Associated with Maternal SSRI Use in Pregnancy

Posted in Misc. Drugs, Paxil Birth Defects, Prozac Birth Defects, Zoloft Birth Defects

Anal atresia, or “imperforate anus,” is a congenital birth defect “in which the opening to the anus is missing or blocked.”[1]  PubMed Health, a prominent online medical encyclopedia curated by the U.S. National Library of Medicine, states that anal atresia may manifest in several different ways: “The rectum may end in a blind pouch that… Continue Reading

Zoloft Linked to Omphalocele Birth Defect

Posted in Paxil Birth Defects, Prozac Birth Defects, Zoloft Birth Defects

Omphalocele is a congenital birth defect in which the intestines or other abdominal organs stick out of the baby’s navel, and is considered a type of hernia.  Babies born with omphalocele are at a dramatically increased risk for intestinal infection,[1] and “death of intestinal tissue,”[2] both of which are very serious medical conditions that may… Continue Reading

Limb Reduction Defects Linked to Zoloft, Celexa

Posted in Celexa Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

Limb reduction deficits are congenital (from birth) malformations of the newborn’s body in which one or more of the limbs does not fully develop, either partially or fully, before birth.[1]  The United States Centers for Disease Control and Prevention (CDC) reports that in the general population, about 4 babies in every 10,000 are born born with… Continue Reading

Use of SSRIs during Pregnancy Doubles Risk of PPHN

Posted in Misc. Drugs, Paxil Birth Defects, Prozac Birth Defects, Zoloft Birth Defects

A recent study published in the British Journal of Medicine has investigated the connection between maternal use of selective serotonin reuptake inhibitor drugs (SSRIs) such as Zoloft®, Paxil®, Prozac®, Celexa®, and Lexapro® during pregnancy and the development of persistent pulmonary hypertension in the newborn.  This study, published by Helle Kieler et al. corroborates earlier research… Continue Reading

American Journal of Psychiatry Illustrates Danger of Antidepressant Use during Pregnancy

Posted in Misc. Drugs, Paxil Birth Defects, Prozac Birth Defects, Zoloft Birth Defects

A study published in 2002 in the American Journal of Psychiatry by Dr. Gregory E. Simon, et al. goes great lengths to elucidate the danger of maternal use of antidepressant drugs during pregnancy.  In this study, Simon gathered data from the Group Health Corporation, “a prepaid health plan serving approximately 400,000 members in Washington State.”[1]… Continue Reading

Study Shows Danger of SSRIs When Used During Pregnancy

Posted in Misc. Drugs, Paxil Birth Defects, Prozac Birth Defects, Zoloft Birth Defects

A recent study published in the Archives of General Psychiatry set out to determine whether it was worse for a developing fetus to be exposed to antidepressant drugs during gestation or to be carried to term by a mother-to-be who suffered from depression during pregnancy.  This study, published by Dr. Tim F. Oberlander et al…. Continue Reading

Study Shows Antidepressant Use During Pregnancy Leads to More Birth Defects

Posted in Misc. Drugs, Paxil Birth Defects, Prozac Birth Defects, Zoloft Birth Defects

In 2010, a Danish study published in the medical journal Clinical Epidemiology set out to evaluate the danger posed to infants born to mothers who used selective serotonin reuptake inhibitors (SSRIs, a new class of antidepressant drugs including Zoloft®, Paxil®, and Prozac®) during early pregnancy. The study, published by Jette B. Kornum et al. compared… Continue Reading