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Category Archives: SSRI Birth Defects

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SSRIs linked to “abnormal development” of fetus

Posted in SSRI Birth Defects

In 2012, C.M. Nijenhuis and a team from University of Groningen (Groningen, The Netherlands) published a study titled “Disturbed development of the enteric nervous system after in utero exposure of selective serotonin re-uptake inhibitors and tricyclic antidepressants. Part 1: Literature review.” in British Journal of Clinical Pharmacology.  There, the link between gestational exposure to selective… Continue Reading

2009 – Preterm birth again linked to SSRI exposure before birth

Posted in SSRI Birth Defects

Recently, I found an article titled “Risk of preterm delivery and other adverse perinatal outcomes in relation to maternal use of psychotropic medications during pregnancy.” that originally appeared in the December 2009 edition of American Journal of Obstetrics and Gynecology.  Published by R. Calderon-Margalit and a team from The University of Washington School of Public… Continue Reading

SSRIs in pregnancy linked to 12-fold increased risk for preterm birth

Posted in SSRI Birth Defects

Today, I came across an article published in a 2011 edition of Journal of Midwifery and Women’s Health by G. Latendresse and a team of researchers from The University of Utah College of Nursing (Salt Lake City) titled “Maternal corticotropin-releasing hormone and the use of selective serotonin reuptake inhibitors independently predict the occurrence of preterm… Continue Reading

2011 – Low gestational age linked to SSRI exposure, not maternal depression

Posted in SSRI Birth Defects

Titled “Newborn neurobehavioral patterns are differentially related to prenatal maternal major depressive disorder and serotonin reuptake inhibitor treatment.”, an article by A.L. Salisbury and a team from the Warren Alpert Medical School of Brown University, appearing in the December, 2011 edition of Depression and Anxiety, further explores the link between selective serotonin reuptake inhibitor drugs… Continue Reading

Neurological function adversely affected by maternal SSRIs

Posted in SSRI Birth Defects

In May, 2013, N.K. de Vries published an article titled “Early neurological outcome of young infants exposed to selective serotonin reuptake inhibitors during pregnancy: results from the observational SMOK study.” in the medical journal PLoS One.  This Dutch research team explored poor neonatal outcomes linked to selective serotonin reuptake inhibitor drugs (SSRIs). de Vries et… Continue Reading

2011 – Heart development affected by maternal SSRI use

Posted in SSRI Birth Defects

Published in the July, 2011 edition of Pediatric Research, a study by D. Rurak and a team from The University of British Columbia (Vancouver) titled “Third trimester fetal heart rate and Doppler middle cerebral artery blood flow velocity characteristics during prenatal selective serotonin reuptake inhibitor exposure.” examined the relationship between selective serotonin reuptake inhibitor drugs… Continue Reading

Study shows SSRIs affect fetal neurodevelopment

Posted in SSRI Birth Defects

From The Netherlands, a team of medical researchers led by E.J. Mulder published a study titled “Selective serotonin reuptake inhibitors affect neurobehavioral development in the human fetus.” in the September, 2011 edition of Neuropsychopharmacology examining the relationship between exposure to selective serotonin reuptake inhibitor drugs (SSRIs) and adverse birth outcomes. The team states “The aim… Continue Reading

Autism, poor neurodevelopment linked to SSRIs in pregnancy

Posted in SSRI Birth Defects

An article titled “SSRI antidepressants: altered psychomotor development following exposure in utero?” that appeared in the February, 2013 edition of Prescrire International examines additional risks of prenatal exposure to selective serotonin reuptake inhibitor drugs (SSRIs).  To be clear, a number of other studies have linked adverse birth outcomes linked to SSRI exposure in years passed…. Continue Reading

2013 – Researchers show that SSRIs (not maternal depression) cause poor neonatal outcomes

Posted in SSRI Birth Defects

Last summer, a team of researchers from University of British Columbia (Vancouver) led by G.E. Hanley published a study titled “Infant developmental outcomes following prenatal exposure to antidepressants, and maternal depressed mood and positive affect.” in Early Human Development.  This study examined the relationship between poor early childhood development and gestational exposure to selective serotonin… Continue Reading

Prozac, Pazil, Zoloft, Celexa linked to Persistent Pulmonary Hypertension of the Newborn (PPHN)

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

Titled “Further findings linking SSRIs during pregnancy and persistent pulmonary hypertension of the newborn: clinical implications.”, this article appearing in the October, 2012 edition of CNS Drugs by M. Galbally et al., identifies persistent pulmonary hypertension of the newborn (PPHN) as a potential consequence of SSRI exposure before birth. Galbally et al. (2012) writes “Persistent… Continue Reading

2006 – Persistent Pulmonary Hypertension Linked to SSRIs in Pregnancy

Posted in SSRI Birth Defects

A team of researchers from Sydney, Australia (led by M.P. Austin) published an article in a December, 2006 edition of Psychological Medicine titled “To treat or not to treat: maternal depression, SSRI use in pregnancy and adverse neonatal effects.” that attempted to clarify negative consequences of prenatal exposure to SSRI drugs like Prozac, Paxil, and… Continue Reading

More research links poor development with SSRI exposure

Posted in SSRI Birth Defects

An article in Early Human Development (February, 2013) by M.V. Smith et al. titled “Neurobehavioral assessment of infants born at term and in utero exposure to serotonin reuptake inhibitors.”, from The Yale School of Medicine delves further into the link between prenatal SSRI exposure and adverse birth outcomes.  Selective serotonin reuptake inhibitor drugs (SSRIs) are… Continue Reading

Autism, developmental delay risk raised 300% with SSRI exposure before birth

Posted in SSRI Birth Defects

This past April, a piece by R.A. Harrington and a team from Johns Hopkins Bloomberg School of Public Health published in Pediatrics titled “Prenatal SSRI Use and Offspring With Autism Spectrum Disorder or Developmental Delay.” further illustrates the link between prenatal exposure to selective serotonin reuptake inhibitor drugs (SSRIs) and increased risk for autism and… Continue Reading

Study finds some babies more likely to have SSRI birth defects than others

Posted in SSRI Birth Defects

Last summer, Developmental Psychobiology published a piece by S. Brummelte and a team from University of British Columbia (Vancouver) titled “Antidepressant use during pregnancy and serotonin transporter genotype (SLC6A4) affect newborn serum reelin levels.” exploring contributing genetic factors to susceptibility for SSRI-induced birth defects.  To-date, a number of studies have shown that in utero exposure… Continue Reading

Study links maternal SSRIs and childhood autism

Posted in SSRI Birth Defects

A New England Journal of Medicine article published in December, 2013 by A. Hviid et al. titled “Use of selective serotonin reuptake inhibitors during pregnancy and risk of autism.” demonstrates further the connection between prenatal exposure to a mother’s selective serotonin reuptake inhibitor drugs (SSRIs) and increased risk for congenital malformations and autism. Hviid et… Continue Reading

Offspring maladaptive with in utero SSRI epxosure

Posted in SSRI Birth Defects

Today, looking through PubMed Health, a medical literature database curated by the United States National Library of Medicine and The National Institutes of Health, I found another article linking poor neonatal outcomes and  to birth defects prenatal exposure to maternal selective serotonin reuptake inhibitor drugs (SSRIs).  This article, titled “Developmental effects of SSRIs: lessons learned… Continue Reading

Increased risk for neonatal morbidity linked to prenatal SSRI exposure

Posted in SSRI Birth Defects

In October, 2012, a team of Swedish researchers (University of Lund) led by B. Källén published an article in Journal of Clinical Psychopharmacology titled “Neonatal complications after maternal concomitant use of SSRI and other central nervous system active drugs during the second or third trimester of pregnancy.”, exploring the range of neonatal complications linked to… Continue Reading

2013 – More researchers find serious risks with antidepressants in pregnancy

Posted in Prozac Birth Defects, SSRI Birth Defects

Titled “The risks of selective serotonin reuptake inhibitor use in infertile women: a review of the impact on fertility, pregnancy, neonatal health and beyond.”, a piece appearing in the January, 2013 edition of Human Reproduction by A.D. Domar and a team from Harvard Medical School provides important insight into the link between gestational exposure to… Continue Reading

Heart defects linked to prenatal Prozac exposure

Posted in Prozac Birth Defects, SSRI Birth Defects

In July, 2008, a team of researchers from The Netherlands led by CW Noorlander published a study titled “Modulation of serotonin transporter function during fetal development causes dilated heart cardiomyopathy and lifelong behavioral abnormalities.” in PLoS One.  This article delves further into the link between prenatal exposure to a mother’s selective serotonin reuptake inhibitor drug… Continue Reading

SSRIs in pregnancy linked to increased weight later in child’s life

Posted in SSRI Birth Defects

A 2012 in Reproductive Toxicology by L.E. Grzeskowiak at a team from University of South Australia  (Adelaide) titled “Long term impact of prenatal exposure to SSRIs on growth and body weight in childhood: evidence from animal and human studies.” explores the link between a baby’s exposure to maternal selective serotonin reuptake inhibitor drugs (SSRIs) and… Continue Reading

Another study links autism and maternal use of SSRI drugs in pregnancy

Posted in SSRI Birth Defects

A 2011 article in Archives of General Psychiatry by L.A. Croen and a team of researchers from Kaiser Permanente (a large healthcare company), titled “Antidepressant use during pregnancy and childhood autism spectrum disorders.” examines the relationship between gestational exposure to selective serotonin reuptake inhibitor drugs like Prozac, Zoloft, and Paxil and developmental disorders like autism… Continue Reading

Research highlights heart defects coupled with prenatal SSRI exposure

Posted in SSRI Birth Defects

Published in an August 2012 edition of Early Human Development, an article by K. Lim et al. titled “Third trimester fetal pulmonary artery Doppler blood flow velocity characteristics following prenatal selective serotonin reuptake inhibitor (SSRI) exposure.” further examines the risk for birth defects like persistent pulmonary hypertension of the newborn (PPHN) after exposure to maternal… Continue Reading

Study Shows: Drugs, not maternal illness, increase risk for poor neonatal development

Posted in SSRI Birth Defects

Today, while reading through PubMed, an amazing database of medical literature provided by the United States National Library of Medicine and The National Institutes of Health, I found an article dating back to 2003 titled “Follow-up of children of depressed mothers exposed or not exposed to antidepressant drugs during pregnancy.” originally appearing in The Journal… Continue Reading

2012 – Increased risk for poor birth outcomes with SSRI exposure

Posted in SSRI Birth Defects

Titled “Infant and childhood neurodevelopmental outcomes following prenatal exposure to selective serotonin reuptake inhibitors: overview and design of a Finnish Register-Based Study (FinESSI).”, an article by a team of prominent SSRI-birth defect researchers led by H. Malm (2012) published in BMC Psychiatry makes great strides in elucidating the range of adverse effects of prenatal exposure… Continue Reading