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Category Archives: Prozac Birth Defects

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Prozac, Pazil, Zoloft, Celexa linked to Persistent Pulmonary Hypertension of the Newborn (PPHN)

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

Titled “Further findings linking SSRIs during pregnancy and persistent pulmonary hypertension of the newborn: clinical implications.”, this article appearing in the October, 2012 edition of CNS Drugs by M. Galbally et al., identifies persistent pulmonary hypertension of the newborn (PPHN) as a potential consequence of SSRI exposure before birth. Galbally et al. (2012) writes “Persistent… Continue Reading

2013 – More researchers find serious risks with antidepressants in pregnancy

Posted in Prozac Birth Defects, SSRI Birth Defects

Titled “The risks of selective serotonin reuptake inhibitor use in infertile women: a review of the impact on fertility, pregnancy, neonatal health and beyond.”, a piece appearing in the January, 2013 edition of Human Reproduction by A.D. Domar and a team from Harvard Medical School provides important insight into the link between gestational exposure to… Continue Reading

Heart defects linked to prenatal Prozac exposure

Posted in Prozac Birth Defects, SSRI Birth Defects

In July, 2008, a team of researchers from The Netherlands led by CW Noorlander published a study titled “Modulation of serotonin transporter function during fetal development causes dilated heart cardiomyopathy and lifelong behavioral abnormalities.” in PLoS One.  This article delves further into the link between prenatal exposure to a mother’s selective serotonin reuptake inhibitor drug… Continue Reading

2012 – Range of poor neonatal outcomes linked to SSRIs in pregnancy

Posted in Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

Over the past several decades, drugs like Prozac and Zoloft have come under fire over a connection to birth defects (and host of other negative consequences related to SSRI use in pregnancy).  Recently, I came across a piece by L.E. Grzeskowiak et al. (2012) published in Journal of Clinical Psychopharmacology titled “Neonatal outcomes after late-gestation… Continue Reading

2005 – Study reviews Prozac’s effects on fetal development

Posted in Prozac Birth Defects, SSRI Birth Defects

Published in a 2005 edition of Reproduction, fertility, and development, an article titled “Fluoxetine during pregnancy: impact on fetal development.” by JL Morrison and a team of researchers from University of Adelaide (Australia) explored the connection between prenatal exposure to pregnancySSRI drugs and adverse birth outcomes including birth defects. The team explains that, “Women are… Continue Reading

2007 – Prozac linked to adverse birth outcomes in mice

Posted in Prozac Birth Defects, SSRI Birth Defects

Titled “Behavioral evaluation of male and female mice pups exposed to fluoxetine during pregnancy and lactation.”, an article by SF Lisboa and a team of researchers from State University of Londrina (Londrina, Brazil) that appeared in Pharmacology (2007) illustrates reasons to avoid Prozac use during pregnancy.  For clarity, “fluoxetine” is the chemical name for Prozac…. Continue Reading

2009 – More research links SSRIs with birth defects: heart defects, adverse birth outcomes

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

In 2009, S. Alwan and J.M. Friedman, a research duo from the University of British Columbia in Vancouver, published a study titled “Safety of selective serotonin reuptake inhibitors in pregnancy.” in CNS Drugs that provided important insight into the link between gestational exposure to selective serotonin reuptake inhibitor drugs (such as Prozac, Paxil, and Zoloft)… Continue Reading

2010 – Infantile Hypertrophic Pyloric Stenosis (IHPS) linked to Prozac exposure

Posted in Prozac Birth Defects, SSRI Birth Defects

Today, I came across an article from the Netherlands by M.K. Bakker published in Pharmacoepidemiology and Drug Safety (August, 2010) titled “Fluoxetine and infantile hypertrophic pylorus stenosis: a signal from a birth defects-drug exposure surveillance study.”, a piece that made great strides in elucidating the connection between prenatal exposure to Prozac (fluoxetine) and serious birth… Continue Reading

2010 – Goldenhar syndrome linked with prenatal Prozac exposure

Posted in Prozac Birth Defects, SSRI Birth Defects

In July 2010, a team of Lebanese published a study titled “Goldenhar syndrome associated with prenatal maternal Fluoxetine ingestion: Cause or coincidence?” in the medical journal Birth Defects Research reviewing a congenital malformation linked to prenatal Prozac (fluoxetine) exposure.  That team, led by C. Farra, was the first to associate goldenhar syndrome with Prozac, though… Continue Reading

Prozac-exposed children more likely to have neonatal abstinence syndrome

Posted in Prozac Birth Defects, SSRI Birth Defects

A study published in the September, 2004 edition of The international journal of neuropsyhopharmacology titled “A pilot study of newer antidepressant concentrations in cord and maternal serum and possible effects in the neonate.” by J. Rampono et al. provides further insight into the connection between gestational exposure to selective serotonin reuptake inhibitor drugs and adverse… Continue Reading

1997 – Spontaneous abortion seen in 14% of prenatal SSRI exposures

Posted in Prozac Birth Defects, SSRI Birth Defects

Researching the connection between prenatal Prozac exposure and birth defects this morning, I found an article by D.J. Goldstein et al., titled “Effects of first-trimester fluoxetine exposure on the newborn.”  This article, appearing in the May, 1997 edition of Obstetrics and Gynecology, provides important insight into the connection between gestational SSRI exposure and adverse birth… Continue Reading

1996 – Prozac linked to birth defects, premature birth, low birth weight, adverse outcomes

Posted in Prozac Birth Defects, SSRI Birth Defects

Recently, I found an article titled “Birth outcomes in pregnant women taking fluoxetine.”, appearing in the October 1996 edition of The New England Journal of Medicine, amounting to one of the oldest articles studying the link between gestational Prozac exposure and adverse birth outcomes.  Over the past two decades, many studies have been published linking… Continue Reading

1996 – Adverse birth outcomes seen with prenatal Prozac exposure

Posted in Prozac Birth Defects, SSRI Birth Defects

In 1996, C.D. Chambers et al. published a study titled “Birth outcomes in pregnant women taking fluoxetine.” in The New England Journal of Medicine studying the effects of prenatal exposure to Prozac (fluoxetine).  Many studies since have demonstrated that babies born to mothers who used Prozac before birth are much more likely to be born… Continue Reading

2005 – Adverse birth outcomes linked to prenatal SSRI exposure

Posted in Prozac Birth Defects, SSRI Birth Defects

In 2005, T.F. Oberlander et al. published results of a study titled “Pain reactivity in 2-month-old infants after prenatal and postnatal serotonin reuptake inhibitor medication exposure.” in the medical journal Pediatrics, demonstrating further the risks of prenatal exposure to selective serotonin reuptake inhibitor drugs, or “SSRIs.” The team writes “In this prospective study, we examined… Continue Reading

Three more studies illustrate risks of Prozac during pregnancy

Posted in Prozac Birth Defects, SSRI Birth Defects

This morning, I found three more studies discussing the risks of prenatal Prozac exposure.  One  discuses long-term effects, one describes behavioral effects, and another describes birth defects “caused” by Prozac.  For other studies on the risks of Prozac exposure during pregnancy, follow the preceding link. A team of researchers led by V. Kiryanova (2013) published… Continue Reading

2007 – Birth defects seen in rats exposed to Prozac

Posted in Prozac Birth Defects, SSRI Birth Defects

Today, I came across a 2007 study linking adverse birth outcomes with exposure to Prozac (fluoxetine) during pregnancy.  This article, by E. Fornaro et al., a team of Canadian medical researchers, titled “Prenatal exposure to fluoxetine induces fetal pulmonary hypertension in the rat.” published in American Journal of Respiratory and Critical Care Medicine links persistent… Continue Reading

2012 – Prozac exposure and adverse effects on baby rats, including low birth weight

Posted in Prozac Birth Defects, SSRI Birth Defects

In 2012, an article by B.B. McAllister et al. published in Neuroscience titled “Behavioural outcomes of perinatal maternal fluoxetine treatment.” further illustrates the risks tied to prenatal fluoxetine (Prozac) exposure, demonstrating resulting developmental issues in gestational mice. The team writes “During and following pregnancy, women are at considerable risk of experiencing depression. For treatment, selective… Continue Reading

2009 – Research shows SSRIs cross placenta

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

Published in May, 2009 in Pharmacopsychiatry by a team of Australian researchers led by J. Rampono, an article titled “Placental transfer of SSRI and SNRI antidepressants and effects on the neonate.” provides further evidence that drugs such as Celexa, Lexapro, Prozac, Paxil, Zoloft, Effexor and others may cross the placenta and affect a developing fetus…. Continue Reading

Three more studies link Celexa, SSRIs to adverse birth outcomes

Posted in Celexa Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

Over the past several decades, a number of studies have linked Celexa exposure and birth defects.  This morning, I found several more, some of which are summarized below.  For more articles demonstrating the connection between birth defects and Celexa, follow the preceding link. In a 2013 edition of Fetal and Pediatric Pathology, an article by… Continue Reading

2008 – Prozac linked to perinatal complications

Posted in Prozac Birth Defects, SSRI Birth Defects

In December, 2008, a team of researchers from the Baskent University Faculty of Medicine, in Ankara, Turkey, led by F. Alehan, published a study titled “Prolonged neonatal complications after in utero exposure to fluoxetine.” in The Journal of Maternal-Fetal and Neonatal Medicine.  This article provided further evidence that prenatal exposure to selective serotonin reuptake inhibitor… Continue Reading

Five more studies illustrate the danger of prenatal exposure to SSRI drugs

Posted in Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects

This morning, I found a number of studies on PubMed (a medical research database curated by the US National Library of Medicine and National Institutes of Health) that linked prenatal exposure to selective serotonin reuptake inhibitor drugs (“SSRIs,” for short) and adverse birth outcomes.  Over the past two decades, many researchers have linked SSRI exposure… Continue Reading

Early pregnancy use of Prozac and Paxil linked to birth defects, “adverse perinatal outcome”

Posted in Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects

Over the past several decades, a number of studies have linked selective serotonin reuptake inhibitors (SSRIs) to a range of birth defects: neurological birth defects including spina bifida, cardiovascular birth defects including tricuspid atresia, craniofacial defects like cleft palate, developmental disorders such as autism, and neonatal adaptation disorders.  As the manufacturers of many SSRIs have… Continue Reading

2012 – Study finds birth defects linked to prenatal Paxil, Prozac exposure

Posted in Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects

Published in the December, 2012 edition of Therapeutic Drug Monitoring, an article by H. Malm titled “Prenatal exposure to selective serotonin reuptake inhibitors and infant outcome.”  provides further insight into the connection between prenatal exposure to selective serotonin reuptake inhibitor (SSRI) drugs and adverse birth outcomes.  Malm has done a great deal of research on… Continue Reading

2012 – SSRIs associated with spontaneous abortion

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

Studies have shown that women suffering from depression during pregnancy can put the child at risk of developing malformations.  As such, selective serotonin reuptake inhibitors (SSRIs) are most commonly prescribed to the mother to avoid such complications.  Unfortunately, using these drugs during pregnancy may also put the child at risk of malformations.  To date, the… Continue Reading