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Category Archives: Propecia / Proscar

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Several studies link finasteride (Proscar, Propecia) to sexual dysfunction

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Since the early 1990s, scientists and medical researchers have found that finasteride use is linked to sexual dysfunction in the form of erectile dysfunction, loss of libido, ejaculation disorder, and other ailments.  This chemical is the active chemical in the hair loss drug Propecia (finasteride 1mg) and the benign prostatic hyperplasia (BPH) drug, Proscar (finasteride… Continue Reading

Study shows that long-term sexual side effects of finasteride are linked to anxiety, depression

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Here is an excerpt from a 2013 article appearing in Journal of Sexual Medicine titled “Neuroactive steroid levels are modified in cerebrospinal fluid and plasma of post-finasteride patients showing persistent sexual side effects and anxious/depressive symptomatology.”: “Observations performed in a subset of subjects treated with finasteride (an inhibitor of the enzyme 5α-reductase) for male pattern… Continue Reading

Another study links Proscar and Propecia to depression following sexual side effects

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In the September 2012 edition of Journal of Clinical Psychiatry, medical researcher MS Irwig published a study titled “Depressive symptoms and suicidal thoughts among former users of finasteride with persistent sexual side effects.”, illustrating one dimension of the truly devastating effects of Propecia (finasteride 1mg, for hair loss) and Proscar (finasteride 5mg, for benign prostatic… Continue Reading

2014 – Research shows nearly 3-fold increased risk for ejaculation disorder with finasteride (Propecia, Proscar)

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An article published in the April, 2014 edition of Journal of Sexual Medicine by M. Gacci et al. titled “Impact of Medical Treatments for Male Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia on Ejaculatory Function: A Systematic Review and Meta-Analysis.” provides additional support for finasteride’s link to sexual dysfunction.  Finasteride is the active… Continue Reading

2005 – More evidence for the Proscar-sexual side effects link

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In 2005, an article titled “Sexual dysfunction and lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH).” appearing in the medical journal European Urology, provided further evidence of scholarly knowledge of the link between finasteride and sexual dysfunction long before warning labels for the drug were updated. Finasteride is the active chemical in… Continue Reading

2005 – Finasteride “clearly associated with sexual side effects”

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An article published in a 2005 edition of Comprehensive Therapy titled “Noninvasive management of lower urinary tract symptoms and sexual dysfunction associated with benign prostatic hyperplasia in the primary care setting.” makes an important note of the connection between finasteride and sexual side effects.  Finasteride is the active chemical in Proscar, a drug commonly used… Continue Reading

2008 study cites link between finasteride and sexual side effects

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Finasteride is a chemical in a larger class called 5alpha-reductase inhibitors, and is the active chemical in the hair loss drug Propecia (finasteride 1mg), and the benign prostatic hyperplasia drug Proscar (finasteride 5mg).  Recently, a number of scientific studies have demonstrated that finasteride use is linked to adverse sexual effects including erectile dysfunction, ejaculation disorder,… Continue Reading

2010 – Propecia doubles risk for erectile dysfunction

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A 2010 article published in Archives of Dermatology by JM Mella et al. titled “Efficacy and safety of finasteride therapy for androgenetic alopecia: a systematic review.” further demonstrates that finasteride use is linked to sexual side effects.  Finasteride is the active chemical in Alopecia, the BPH drug Proscar, the hair loss drug Propecia, among others…. Continue Reading

2012 – JAMA: “Prostate, Baldness Drugs Linked to Sexual Dysfunction”

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An article published in the May, 2012 edition of Journal of the American Medical Association titled “Prostate, Baldness Drugs Linked to Sexual Dysfunction” provides important insight into the link that Proscar (finasteride 5mg, used to treat BPH) and Propecia (finasteride 1mg, used to treat male pattern hair loss) have with a range of adverse sexual… Continue Reading

April 2012 – FDA Requires PROPECIA and PROSCAR Warning Label Update

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Here is an excerpt from the FDA’s frequently-asked questions page for required the Proscar and Propecia Warning Label Update: Questions and Answers: Finasteride Label Changes “On April 11, 2012, the U.S. Food and Drug Administration (FDA) announced changes to the professional labels for Propecia (finasteride 1 mg) and Proscar (finasteride 5 mg) to expand the… Continue Reading

2012 – Propecia, Proscar linked to sexual side effects

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In a 2012 edition of International Journal of Clinical Practice, an article by SA Kaplan et al. titled “A 5-year retrospective analysis of 5α-reductase inhibitors in men with benign prostatic hyperplasia: finasteride has comparable urinary symptom efficacy and prostate volume reduction, but less sexual side effects and breast complications than dutasteride.” gave important insight into… Continue Reading

2007 – Study shows rate for Proscar side effects higher than warning label

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In 2007, five years before Proscar and Propecia warning labels were required to be updated by the FDA to include information on sexual side effects, an important paper was published in Clinical Therapeutics by MJ Naslund titled “A review of the clinical efficacy and safety of 5alpha-reductase inhibitors for the enlarged prostate.”. This study reviewed… Continue Reading

Tricky language in company-funded Proscar study

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Just a quick note about a finasteride study I recently read in Archives of Internal Medicine.  For clarity, finasteride is the active chemical in the hair loss drug Propecia and the benign prostatic hyperplasia (BPH) drug Proscar, and both Propecia and Proscar are manufactured by Merck & Co., Inc. This study, titled “Maintenance of clinical… Continue Reading

1996 – Study links finasteride and sexual side effects long before warning labels updated

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Though the warning labels for Propecia (finasteride 1mg) and Proscar (finasteride 5mg) were not updated to include information about long-term sexual side effects until April, 2012, research has been available to the public for over a decade that shows finasteride is connected with such adverse effects.  Here, we discuss an article appearing in the November,… Continue Reading

1999 – Finasteride linked to adverse sexual effects

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An article from the October, 1999 edition of Urology went great lengths to provide important insight into the connection between finasteride (the active chemical in Propecia, Proscar, and other drugs) and sexual side-effects.  This article is titled “Effect of finasteride on bother and other health-related quality of life aspects associated with benign prostatic hyperplasia. PLESS… Continue Reading

2010 – Finasteride linked to range of sexual side-effects

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In 2010, an article appearing in the October edition of medical journal The Cochrane Database of Systematic Reviews titled “Finasteride for benign prostatic hyperplasia.” helps us further understand the connection between use of finasteride (the active chemical in benign prostatic hyperplasia drug Proscar) and adverse sexual side effects. This research team, led by J. Tacklind,… Continue Reading

2011 – Study links Propecia, Proscar to adverse sexual side effects

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Published in 2011 – over a year prior to Propecia Warning Label Updates, a paper by A.M. Traish et al. titled “Adverse side effects of 5α-reductase inhibitors therapy: persistent diminished libido and erectile dysfunction and depression in a subset of patients.” illustrated important connections between chemicals like finasteride (the active ingredient in drugs Propecia and… Continue Reading

2013 – New ED in 5-9% of finasteride patients (Propecia, Proscar)

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Published in the January, 2013 edition of Expert Opinion on Drug Safety, an article by S. Gur and a team of researchers from Tulane University (New Orleans) titled “Effects of 5-alpha reductase inhibitors on erectile function, sexual desire and ejaculation.” provides important insight into the connection between finasteride (Propecia, Proscar, others) and adverse sexual side… Continue Reading

2006 – Research shows:: finasteride linked to sexual side effects

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In 2006, an article by F. Giuliano titled “Impact of medical treatments for benign prostatic hyperplasia on sexual function.” published in BJU International helps elucidate the link between finasteride (the active chemical in Propecia, Proscar, and other drugs) and adverse sexual side effects — Proscar is a finasteride-containing drug used commonly in the treatment of… Continue Reading

2011 – Many men using Propecia suffer adverse sexual side effects

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A 2011 article by M.S. Irwig and S. Kolukula, a pair of researchers from The George Washington University, titled “Persistent sexual side effects of finasteride for male pattern hair loss.” demonstrates that sexual side effects of finasteride use often do not subside when drug use is discontinued.  For clarity, finasteride is the active chemical in… Continue Reading

2003: Study shows Proscar doubles risk for sexual side effects

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In 2003, a study by H. Wessells et al., a team from The University of Washington in Seattle, titled “Incidence and severity of sexual adverse experiences in finasteride and placebo-treated men with benign prostatic hyperplasia.” provided an important early illustration of the connection between drugs containing finasteride (such as Propecia and Proscar) and sexual side-effects…. Continue Reading

2008 – Journal of Sexual Medicine: Connection between finasteride and sexual side effects “apparent”

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A 2008 article titled “5-alpha reductase inhibitors and erectile dysfunction: the connection.” by F. Erdemir et al. in Journal of Sexual Medicine provides important insight into the link between finasteride (the active chemical in hair loss drug Propecia and BPH drug Proscar) and adverse sexual side-effects. The authors state “Benign prostatic hyperplasia (BPH) is a… Continue Reading

2013 – Journal of Urology: Proscar, Propecia linked to adverse sexual side effects

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In 2013, an article titled “Change in Sexual Function in Men with Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia Associated with Long-Term Treatment with Doxazosin, Finasteride and Combined Therapy.” by C.W. Fwu et al. published in The Journal of Urology illustrates the connection between finasteride, the active chemical in Propecia, Proscar, and other drugs, and persistent… Continue Reading