Header graphic for print
Dangerous Drugs & Medical Devices News & Commentary on Prescription Drug & Medical Device Lawsuits

Category Archives: Paxil Birth Defects

Subscribe to Paxil Birth Defects RSS Feed

Prozac, Pazil, Zoloft, Celexa linked to Persistent Pulmonary Hypertension of the Newborn (PPHN)

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

Titled “Further findings linking SSRIs during pregnancy and persistent pulmonary hypertension of the newborn: clinical implications.”, this article appearing in the October, 2012 edition of CNS Drugs by M. Galbally et al., identifies persistent pulmonary hypertension of the newborn (PPHN) as a potential consequence of SSRI exposure before birth. Galbally et al. (2012) writes “Persistent… Continue Reading

2009 – Paxil, SSRIs linked to serious birth defects and poor early adaptation

Posted in Paxil Birth Defects, SSRI Birth Defects

Looking through articles today at PubMed Health, a service of the United States National Library of Medicine and The National Institutes of Health, I found a piece titled “The management of depression during pregnancy: a report from the American Psychiatric Association and the American College of Obstetricians and Gynecologists.” published by K.A. Yonkers et al…. Continue Reading

2009 – More research links SSRIs with birth defects: heart defects, adverse birth outcomes

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

In 2009, S. Alwan and J.M. Friedman, a research duo from the University of British Columbia in Vancouver, published a study titled “Safety of selective serotonin reuptake inhibitors in pregnancy.” in CNS Drugs that provided important insight into the link between gestational exposure to selective serotonin reuptake inhibitor drugs (such as Prozac, Paxil, and Zoloft)… Continue Reading

2008 – Paxil exposure shows reduced birth weight in rat model

Posted in Paxil Birth Defects, SSRI Birth Defects

In 2008, a team of Dutch researchers led by D.L. Van den Hove published a study in Neonatology titled “Prenatal maternal paroxetine treatment and neonatal mortality in the rat: a preliminary study.” evaluating the perinatal effects of gestational exposure to Paxil (paroxetine). These researchers write, “Recent evidence has shown that prenatal maternal stress has negative… Continue Reading

2011 – Heart defects linked to prenatal Paxil exposure, again

Posted in Paxil Birth Defects, SSRI Birth Defects

Today, I came across an article from the March, 2011 edition of Journal of Population Therapeutics and Clinical Pharmacology titled “The effect of ascertainment bias in evaluating gestational antidepressant exposure.” that helps illustrate the link between gestational exposure to selective serotonin reuptake inhibitor drugs and birth defects, heart defects in particular. Here is the abstract… Continue Reading

2009 – Research shows SSRIs cross placenta

Posted in Celexa Birth Defects, Effexor Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

Published in May, 2009 in Pharmacopsychiatry by a team of Australian researchers led by J. Rampono, an article titled “Placental transfer of SSRI and SNRI antidepressants and effects on the neonate.” provides further evidence that drugs such as Celexa, Lexapro, Prozac, Paxil, Zoloft, Effexor and others may cross the placenta and affect a developing fetus…. Continue Reading

Three more studies link Celexa, SSRIs to adverse birth outcomes

Posted in Celexa Birth Defects, Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects, Zoloft Birth Defects

Over the past several decades, a number of studies have linked Celexa exposure and birth defects.  This morning, I found several more, some of which are summarized below.  For more articles demonstrating the connection between birth defects and Celexa, follow the preceding link. In a 2013 edition of Fetal and Pediatric Pathology, an article by… Continue Reading

2004 – Risk for low birth weight, preterm birth doubled with Paxil exposure

Posted in Paxil Birth Defects, SSRI Birth Defects

In 2004, an article by B. Källén, a Swedish researcher, titled “Neonate characteristics after maternal use of antidepressants in late pregnancy.” in Archives of Pediatrics and Adolescent Medicine provides insight into the danger of perinatal exposure to selective serotonin reuptake inhibitor drugs (SSRIs). The stated objective was “To investigate neonatal outcomes in 997 infants (987… Continue Reading

2006 – Case of neonatal exposure to Paxil illustrated

Posted in Paxil Birth Defects, SSRI Birth Defects

In 2006, a team of Spanish medical researchers published a report titled “[Neonatal withdrawal syndrome to selective serotonin reuptake inhibitors: case report and literature review].” in Revista de Neurologica, wherein a child who suffered SSRI withdrawal symptoms after birth is presented along with a review of relevant literature.  “SSRI” stands for selective serotonin reuptake inhibitor… Continue Reading

2002 – Babies exposed to Paxil before birth 10 times more likely to have adverse birth outcome

Posted in Paxil Birth Defects, SSRI Birth Defects

A 2002 piece published by A.M. Costei and a team of medical researchers from Toronto in the medical journal Archives of Pediatrics and Adolescent Medicine tited “Perinatal outcome following third trimester exposure to paroxetine.” further demonstrates possible adverse effects of in utero exposure to Paxil.  (“Paroxetine” is the chemical name for Paxil, a selective serotonin… Continue Reading

2006 – FDA Warns Public on Paxil Danger for Neonates

Posted in Paxil Birth Defects, SSRI Birth Defects

In the March-April 2006 edition of Consumer Magazine (of the United States Food and Drug Administration), an important update was provided regarding the safety of selective serotonin reuptake inhibitors for developing babies. Here is the full update, titled “Paxil and the Risk of Birth Defects”: “Early results of new studies for Paxil (paroxetine) suggest that… Continue Reading

Five more studies illustrate the danger of prenatal exposure to SSRI drugs

Posted in Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects

This morning, I found a number of studies on PubMed (a medical research database curated by the US National Library of Medicine and National Institutes of Health) that linked prenatal exposure to selective serotonin reuptake inhibitor drugs (“SSRIs,” for short) and adverse birth outcomes.  Over the past two decades, many researchers have linked SSRI exposure… Continue Reading

Many studies link Paxil, SSRI exposure to adverse birth outcomes

Posted in Paxil Birth Defects, SSRI Birth Defects

Looking through PubMed, a medical literature database curated by the National Library of Medicine and the US National Institutes of Health this morning, I found a number of articles citing the link between SSRI drug use during pregnancy and the risk for adverse birth outcomes.  (For other articles I’ve written on the connection between SSRIs… Continue Reading

2010 – Risk for Atrial Septal Defect Dramatically Increased by Prenatal Paxil Exposure

Posted in Paxil Birth Defects, SSRI Birth Defects

An article published in the February, 2010 edition of the medical journal Birth Defects Research titled “First-trimester use of paroxetine and congenital heart defects: a population-based case-control study.” provides further evidence for the connection between paroxetine (Paxil) and cardiovascular birth defects. This study, conducted by M.K. Bakker et al., a Dutch research team, “performed a… Continue Reading

2010 – Infant suffers neonatal adaptation syndrome after gestational exposure to Paxil

Posted in Paxil Birth Defects, SSRI Birth Defects

An article by Laura Pogliani et al. (2010) titled “Paroxetine and neonatal withdrawal syndrome” published in BMJ Case Reports reports on a newborn who suffered neonatal withdrawal syndrome after prenatal exposure to paroxetine (Paxil). Here is the abstract of that article: “We report a case of neonatal withdrawal syndrome after in utero exposure to paroxetine… Continue Reading

2011 – Depacon, SSRIs advised against during pregnancy citing defects and autism

Posted in Depacon / Depakene / Depakote, Paxil Birth Defects, SSRI Birth Defects

In recent years, a number of studies have demonstrated that Depacon (sodium valproate) use during pregnancy is linked to increased risk for a range of serious birth defects.  This epilepsy drug by Abbott Laboratories, Inc. is often safe, but has been linked to autism, neurological birth defects, heart defects, craniofacial birth defects, and a number… Continue Reading

2010 – Paxil, other SSRI drugs linked to serious birth defects

Posted in Paxil Birth Defects, SSRI Birth Defects

A French team of researchers led by S. Favrelière et al. published an article in L’Encephale titled “Treatment of depressed pregnant women by selective serotonin reuptake inhibitors: risk for the foetus and the newborn” in June, 2010 and provided further insights into the risks associated with selective serotonin reuptake inhibitor (SSRI) use during pregnancy posed… Continue Reading

Early pregnancy use of Prozac and Paxil linked to birth defects, “adverse perinatal outcome”

Posted in Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects

Over the past several decades, a number of studies have linked selective serotonin reuptake inhibitors (SSRIs) to a range of birth defects: neurological birth defects including spina bifida, cardiovascular birth defects including tricuspid atresia, craniofacial defects like cleft palate, developmental disorders such as autism, and neonatal adaptation disorders.  As the manufacturers of many SSRIs have… Continue Reading

2012 – American Family Physician: “Paroxetine Use Should Be Avoided During Pregnancy”

Posted in Paxil Birth Defects, SSRI Birth Defects

Published on April 15th, 2012, an important letter to the editor of American Family Physician was sent by Dr. Brian Budenholzer that cautioned against Paxil use during pregnancy.  (Accordingly, his piece was titled “Paroxetine Use Should Be Avoided During Pregnancy”.)  As it is relatively short, I have chosen to include it in its entirety below…. Continue Reading

2014 – Paxil exposure dramatically raises risk for birth defects

Posted in Paxil Birth Defects, SSRI Birth Defects

An article published March 11, 2014 in BJOG: an international journal of obstetrics and gynaecology by L. Ban et al., a team from The University of Nottingham in the United Kingdom, titled “Maternal depression, antidepressant prescriptions, and congenital anomaly risk in offspring: a population-based cohort study.” provides insight into the connection between neonatal exposure to… Continue Reading

2012 – Study finds birth defects linked to prenatal Paxil, Prozac exposure

Posted in Paxil Birth Defects, Prozac Birth Defects, SSRI Birth Defects

Published in the December, 2012 edition of Therapeutic Drug Monitoring, an article by H. Malm titled “Prenatal exposure to selective serotonin reuptake inhibitors and infant outcome.”  provides further insight into the connection between prenatal exposure to selective serotonin reuptake inhibitor (SSRI) drugs and adverse birth outcomes.  Malm has done a great deal of research on… Continue Reading

2012 – Paxil linked to increased rate for heart defects

Posted in Paxil Birth Defects, SSRI Birth Defects

In 2012, more research connected Paxil (paroxetine) to increased rates of cardiac malformations – that is, birth defects of the heart.  In this study, titled “Paroxetine use during pregnancy and perinatal outcomes including types of cardiac malformations in Quebec and France: a short communication.” by A. Bérard et al. in that year’s July edition of… Continue Reading

2010 – Canadian study shows Paxil, Effexor raise risk for spontaneous abortion

Posted in Effexor Birth Defects, Paxil Birth Defects, SSRI Birth Defects

In 2010, an article published in Canadian Medical Association Journal titled “Use of antidepressants during pregnancy and the risk of spontaneous abortion.” illustrated the link between SSRI use during pregnancy and increased risk for spontaneous abortion. This study, led by H.R. Nakhai-Pour of The University of Montreal, “obtained data from the Quebec Pregnancy Registry for… Continue Reading

2010 – Paxil, Effexor dramatically raise risk for spontaneous abortion

Posted in Effexor Birth Defects, Paxil Birth Defects, SSRI Birth Defects

A recent article by P. Broy et al. published in Current Drug Delivery titled “Gestational exposure to antidepressants and the risk of spontaneous abortion: a review.” provides important insight into the connection between in vitro exposure to SSRI drugs and spontaneous abortion.  SSRI drugs are a relatively new class of antidepressant medications, which aim to… Continue Reading