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Category Archives: Depacon / Depakene / Depakote

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2014 – Birth defects risk increased 250% with Depacon / Depakene / Depakote

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In recent years, dozens of studies have been published illustrating an increased risk for birth defects linked to antiepileptic drugs containing sodium valproate such as Depacon, Depakene, and Depakote.  While these drugs are effective in the mitigation of seizures, the risks posed to developing babies cannot go overlooked.  Here, I will summarize one such study… Continue Reading

Risk for birth defects 47% higher with prenatal exposure to Depacon, Depakene, or Depakote

Posted in Depacon / Depakene / Depakote

In January of last year, a team of researchers led by E. Campbell published an article in Epilepsia titled “Recurrence risk of congenital malformations in infants exposed to antiepileptic drugs in utero.”, marking yet another piece of professional research illustrating the risks of prenatal exposure to drugs containing sodium valproate such as Depacon, Depakene, and… Continue Reading

Study shows: Depacon lifts risk for autism 300%

Posted in Depacon / Depakene / Depakote

Today, I found another article by G. Veiby and a team from The University of Bergen in Bergen, Norway that demonstrates the danger posed to children exposed to valproate in utero.  Valproate (sodium valproate, other formations) is the active chemical in a number of antiepileptic drugs such as Depacon, Depakote, and Depakene.  The article I… Continue Reading

2011 – Birth defect risk “significantly higher” with Depacon, Depakene, or Depakote exposure before birth

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In July, 2011, Lancet Neurology published an article titled “Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry.” that was written by a team from Stockholm led by T. Tomson.  This study is yet another example of peer-reviewed research demonstrating that serious risks are posed to… Continue Reading

Huge birth defect increase with Depacon / Depakene / Depakote in pregnancy

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Today, I came across an article from the February, 2012 edition of The Australian and New Zealand Journal of Obstetrics and Gynecology published by F.J. Vajda and a team of researchers at University of Melbourne (Australia).  In their piece, titled “The prescribing of antiepileptic drugs for pregnant Australian women.” Vajda et al. explore further the… Continue Reading

JAMA: Autism risk 500% increased with Depakote, Depakene, and Depacon in utero

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In the April, 2013 edition of JAMA, an article titled “Prenatal valproate exposure and risk of autism spectrum disorders and childhood autism.” from a Danish team led by J. Christensen evaluated the risks of prenatal exposure to the antiepileptic Depacon.  Because Abbott Laboratories, the manufacturer of this drug, failed time and again to warn of… Continue Reading

Birth defects at significantly higher rate with Depacon, Depakene

Posted in Depacon / Depakene / Depakote

Titled “Malformation risks of antiepileptic drugs in pregnancy: a prospective study from the UK Epilepsy and Pregnancy Register.”, an article by J. Morrow and a team from Belfast (UK) published in the February, 2006 edition of Journal of Neurology, Neurosurgery, and Psychiatry aimed to “assess the relative risk of major congenital malformation (MCM) from in… Continue Reading

2014 – Increased risk for birth defects seen with Depakote exposure

Posted in Depacon / Depakene / Depakote

In July, 2014, a team of Norwegian researchers led by K.O. Nakken published an article in Tidsskr Nor Laegeforen titled “Antiepileptic drugs and congenital malformations”, evaluating the consequences of prenatal exposure to epilepsy drugs containing sodium valproate, such as Depacon, Depakene, and Depakote (Abbott Laboratories, Inc.).  To-date, dozens of studies have demonstrated that a dramatically-increased… Continue Reading

2008 – Epilepsy drugs with valproate linked to higher risk of birth defects, low IQ

Posted in Depacon / Depakene / Depakote

From Stockholm, Sweden, a 2008 piece titled “Teratogenic effects of antiepileptic drugs.” and appearing in the medical journal, Seizure, by T. Tomson et al. yet again demonstrates the postnatal risks of prenatal exposure to epilepsy drugs containing sodium valproate such as Depakote, Depakene, and Depacon (Abbott Laboratories, Inc.). Here, it is stated that “The use… Continue Reading

Harvard: Depacon, Depakote, Depakene linked to poor birth outcomes

Posted in Depacon / Depakene / Depakote

In recent years, a number of studies have shown that prenatal exposure to sodium valproate (the active ingredient in epilepsy drugs Depacon, Depakene, and Depakote) is linked to increased risk for birth defects.  Here, I’ll summarize one such study, titled “Differential effects of antiepileptic drugs on neonatal outcomes.” by P.B. Pennell and a team from… Continue Reading

1992 – Japan finds Depakote, Depakene, Depacon associated with higher birth defect rate

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Titled “Malformation in infants of mothers with epilepsy receiving antiepileptic drugs.”, a piece of Japanese medical research by S. Kaneko et al. published in April, 1992 helps show just how long it has been known that prenatal exposure to epilepsy drugs containing valproate is linked to birth defects.  Depacon, Depakote, and Depakene are top examples… Continue Reading

Finnish Research Shows: Depakote Linked to Birth Defects

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In May, 2013, a Finnish team of medical researchers led by M. Aratma published a study in Drug Safety titled “Effects of maternal epilepsy and antiepileptic drug use during pregnancy on perinatal health in offspring: nationwide, retrospective cohort study in Finland.”.  This piece further elucidated the link between prenatal exposure to antiepileptic drugs such as… Continue Reading

2003 – AEDs with valproate linked to neurological birth defects

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In a 2003 edition of Epilepsia, a piece titled “Clinical care of pregnant women with epilepsy: neural tube defects and folic acid supplementation.” by M.S. Yerby and a team from North Pacific Epilepsy Research in Portland, Oregon demonstrated that a child’s in utero exposure to maternal antiepileptic drugs (particularly those containing valproate – Depakote, Depakene,… Continue Reading

2013 – Neurological and heart defects linked to Depakote

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A piece by medical researchers led by F.J. Vajda published in Acta Neurol Scand. (October, 2013), titled “Associations between particular types of fetal malformation and antiepileptic drug exposure in utero.” lives up to its title and provides more insight into the link between in utero exposure to epilepsy medication (Depacon, Depakene, and Depakote by Abbott… Continue Reading

2009 – More research links Depakote (and other AEDs) to birth defects

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Appearing in the July-August, 2009 edition of the Spanish medical journal, Neurologia, a piece titled “Malformations and fetal death in the Spanish antiepileptic drug and pregnancy registry: results at 6 years” by M. Martinez Ferri et al. aimed to “study the incidence of major congenital malformations (MCM) /and/or fetal-perinatal death (MFP) and determine his relationship… Continue Reading

2002 – Research shows AED exposure lifts rate of neonatal morbidity and birth defects

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In April, 2002, a team of medical researchers from Aberdeen (UK) led by J.C. Dean published a study titled “Long term health and neurodevelopment in children exposed to antiepileptic drugs before birth.” in Journal of Medical Genetics investigating the link between neonatal and later childhood morbidity “in children exposed to antiepileptic drugs [AEDs] in utero.”… Continue Reading

Depakote, other AEDs again linked to birth defects

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An article appearing in the May, 2010 edition of Epilepsia titled “The teratogenic risk of antiepileptic drug polytherapy.” by F.J. Vajda and a team from Royal Melbourne Hospital and University of  Melbourne (Australia) further explores the connection between antiepileptic drugs containing sodium valproate such as Depacon, Depakene, and Depakote and increased risk for congenital malformations…. Continue Reading

2011 – Depacon, Depakene, Depakote exposure linked to poor language skills

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In February, 2011, C. Nadebaum and a British research team published a piece in Neurology titled “Language skills of school-aged children prenatally exposed to antiepileptic drugs.” that provides important insight into the connection between antiepileptic drugs containing sodium valproate (Depacon, Depakene, and Depakote) and birth defects. Nadebaum et al. (2011) state “Fetal exposure to some… Continue Reading

1992 – Study links Depakote and birth defects

Posted in Depacon / Depakene / Depakote

Back in 1992, a French research team led by C. Dravet published a piece in Neurology titled “Epilepsy, antiepileptic drugs, and malformations in children of women with epilepsy: a French prospective cohort study.” that illuminated risks of prenatal exposure to anti-seizure drugs Depacon, Depakene, and Depakote (Abbott Laboratories).  Since, the US FDA has warned of… Continue Reading

2005 – Higher rate of birth defects with Depacon in pregnancy

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A 2005 article in Acta Neurologica Scandinavica by F.J. Vajda and a team from University of Melbourne (Australia) titled “Maternal valproate dosage and foetal malformations.” further elucidates the connection between prenatal exposure to antiepileptic drugs like Depacon and birth defects.  Because the manufacturers (Abbott Laboratories) failed to warn women of this risk in light of… Continue Reading

Depacon Doubles Risk for Birth Defects (At Least)

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Another article demonstrating that prenatal exposure to antiepileptic drugs containing valproate like Depacon is associated with birth defects, “Valproate and the risk for congenital malformations: Is formulation and dosage regime important?” was published in the April, 2012 edition of the medical journal Seizure by E. Mawhinney et al. of Belfast, UK. In light of warnings… Continue Reading

2- to 3-fold increase in birth defects linked to Depacon / Depakote / Depakene

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In 2005, a team of researchers from The University of Pavia (Pavia, Italy) published a study in Lancet Neurology titled “Birth defects after prenatal exposure to antiepileptic drugs.”, yet again demonstrating that in utero exposure to Depacon, Depakene, and Depakote (antiepileptic drugs containing valproate) is linked to an increased risk for spina bifida, other neurological… Continue Reading

2012 – Babies with Depakote exposure more likely to have malformations

Posted in Depacon / Depakene / Depakote

Published in the January, 2012 edition of Journal of Clinical Neuroscience, an article by F.J. Vajda titled “Teratogenicity of the newer antiepileptic drugs–the Australian experience.” provides important insight into the connection between valproate-containing antiepileptic drugs such as Depacon, Depakene, and Depakote (Abbott Laboratories) and birth defects including spina bifida and developmental disorders including Autism. Reviewing… Continue Reading

Depakote raises risk for birth defects 2- to 4-fold

Posted in Depacon / Depakene / Depakote

In recent years, dozens of studies have linked prenatal exposure to the antiepileptic drugs containing valproate (Depacon, Depakene, and Depakote) with birth defects including spina bifida, and developmental disorders such as Autism.  Since the manufacturer of these drugs, Abbott Laboratories, failed time and again to warn women of these risks, Depacon birth defect lawsuits have… Continue Reading